University Of Minnesota

This study tests a new way to use deep brain stimulation (DBS) for Parkinson's disease. Instead of constant high-power pulses, the new method uses lower, timed pulses to reset faulty brain signals. Researchers will check if it is safe and helps with movement problems in 24 adults…

This study tests a special diet designed to meet the protein needs of people with ulcerative colitis while reducing harmful gas produced by gut bacteria. Researchers will measure changes in stool samples from 40 adults with mild to moderate disease. The goal is to see if this die…

This study looks at whether teens with obesity need an intensive lifestyle program (26+ hours) or if a low-intensity program works just as well when they are also taking new obesity medications. About 1,020 teens aged 12 to 17 with a BMI at or above the 95th percentile will take …

This study tests a new way to prevent obesity in adolescents and young adults (ages 18-25) who are at high risk due to family history and higher body weight. Participants will receive lifestyle coaching and possibly medication to help control weight gain. The goal is to stop unhe…

This early-stage study tests a brain stimulation technique for people with long-term nerve pain that hasn't responded to other treatments. About 20 adults with conditions like post-shingles pain or phantom limb pain will receive an implanted device that stimulates specific brain …

This study aims to understand why some former smokers remain at higher risk for lung cancer years after quitting. Researchers will compare how the lungs of 100 former smokers and never-smokers break down a chemical called phenanthrene. The goal is to see if former smokers process…

This study looks at whether shifting text to a healthy part of the eye can help people with central vision loss read faster and more accurately. About 100 adults with dense blind spots in their central vision will read sentences and words with and without this text remapping. The…