New 'Coordinated Reset' brain stimulation aims to improve Parkinson's treatment
NCT ID NCT07340073
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage study will test a new way of using deep brain stimulation (DBS) for Parkinson's disease. Instead of the usual constant high-frequency pulses, this 'Coordinated Reset' approach uses lower-power, patterned stimulation. Researchers want to see if it's safe and can improve movement problems better than standard DBS. The trial will involve 24 adults with Parkinson's who already have or will get a DBS implant.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Deep brain stimulation (DBS) device with coordinated reset pattern
What this could lead to
If successful, this could lead to a more effective and less invasive DBS approach for Parkinson's, potentially reducing side effects like speech or balance problems.
What could go wrong
This is a very early Phase 1 trial with only 24 people, so results may not apply to everyone. The new stimulation pattern might not work better than standard DBS, and there are always surgical risks from the implant procedure.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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