New 'Coordinated Reset' brain stimulation aims to improve Parkinson's treatment

NCT ID NCT07340073

Not yet recruiting Disease control Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This early-stage study will test a new way of using deep brain stimulation (DBS) for Parkinson's disease. Instead of the usual constant high-frequency pulses, this 'Coordinated Reset' approach uses lower-power, patterned stimulation. Researchers want to see if it's safe and can improve movement problems better than standard DBS. The trial will involve 24 adults with Parkinson's who already have or will get a DBS implant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Deep brain stimulation (DBS) device with coordinated reset pattern
What this could lead to: If successful, this could lead to a more effective and less invasive DBS approach for Parkinson's, potentially reducing side effects like speech or balance problems.
What could go wrong: This is a very early Phase 1 trial with only 24 people, so results may not apply to everyone. The new stimulation pattern might not work better than standard DBS, and there are always surgical risks from the implant procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEEP BRAIN STIMULATION PARKINSON'S DISEASE (PD)

More trials for these conditions

Other studies related to the condition(s) this trial covers.