University Of Calgary
Clinical trials sponsored by University Of Calgary, explained in plain language.
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Moxie program aims to slash heart hospital readmissions by 34% in massive alberta trial
Disease control Not yet recruitingThis study tests a program called Moxie that sends weekly health tips by mail and offers a mobile app to help people manage chronic conditions like heart disease, diabetes, and kidney disease. The goal is to see if it reduces the number of times people are readmitted to the hospi…
Phase: NA • Sponsor: University of Calgary • Aim: Disease control
Last updated May 17, 2026 00:53 UTC
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Last-resort virus treatment aims to wipe out untreatable hip infection
Disease control Not yet recruitingThis study tests whether specially designed viruses (bacteriophages) can eliminate a persistent bacterial infection in a hip replacement joint. The single participant has already tried all standard treatments without success. The therapy involves injecting the viruses directly in…
Phase: PHASE1, PHASE2 • Sponsor: University of Calgary • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Microwave scanner could spot ruptured breast implants
Diagnosis Not yet recruitingThis study will test if a microwave imaging device can see breast implants and detect ruptures. Ten women with implants placed at least 6 months ago will get a microwave scan. Researchers will compare the scan images to the known implant size and check if left and right breasts l…
Phase: NA • Sponsor: University of Calgary • Aim: Diagnosis
Last updated May 17, 2026 00:51 UTC
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New genetic test aims to reduce unnecessary thyroid surgeries
Diagnosis Not yet recruitingThis study looks at whether a genetic test called Thyroid GuidePx® can help doctors and patients with papillary thyroid cancer make better treatment choices. About 85 adults with small thyroid tumors and no signs of spread will take the test before surgery. Researchers will see i…
Sponsor: University of Calgary • Aim: Diagnosis
Last updated May 15, 2026 12:07 UTC
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Smart bug test aims to stop deadly pneumonia in ventilated ICU patients
Prevention Not yet recruitingThis study tests a new way to prevent ventilator-associated pneumonia (VAP), a common and serious infection in ICU patients on breathing machines. Researchers will use a rapid test (about 4 hours) to find harmful bacteria in the airway, then give targeted inhaled antibiotics only…
Phase: PHASE2 • Sponsor: University of Calgary • Aim: Prevention
Last updated May 12, 2026 13:42 UTC
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Magnetic pulses aim to lift MS depression and fatigue
Symptom relief Not yet recruitingThis early-stage study tests whether a non-invasive brain stimulation technique called rTMS is safe and tolerable for treating depression and fatigue in adults with multiple sclerosis (MS). About 20 participants with MS and moderate-to-severe depression will receive daily rTMS se…
Phase: PHASE1 • Sponsor: University of Calgary • Aim: Symptom relief
Last updated May 17, 2026 00:59 UTC
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Ear device could tame debilitating POTS symptoms
Symptom relief Not yet recruitingThis study tests whether a gentle electrical stimulation applied to the ear (auricular vagal neuromodulation) can help people with Postural Orthostatic Tachycardia Syndrome (POTS). POTS causes a rapid heart rate upon standing, along with fatigue, brain fog, and other symptoms. Th…
Phase: NA • Sponsor: University of Calgary • Aim: Symptom relief
Last updated May 17, 2026 00:59 UTC
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New gel may prevent wound problems after breast reduction
Symptom relief Not yet recruitingThis pilot study tests whether a special gel (CO2Lift Pro) can reduce wound breakdown after breast reduction surgery. Ten women will have the gel applied to one breast and a placebo to the other, then be monitored for 12 weeks. The main goal is to see if a larger study is possibl…
Phase: NA • Sponsor: University of Calgary • Aim: Symptom relief
Last updated May 17, 2026 00:50 UTC
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Magic mushroom therapy could ease PTSD in abuse survivors
Symptom relief Not yet recruitingThis study tests whether psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can reduce PTSD symptoms in adults who have survived intimate partner violence. 76 participants will receive either a high or low dose of psilocybin, then attend weekly thera…
Phase: PHASE2 • Sponsor: University of Calgary • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Pre-Surgery boot camp may speed up recovery for men with enlarged prostate
Symptom relief Not yet recruitingThis study looks at whether a 12-week program of pelvic floor exercises, extra health information, and mental health support before prostate surgery can help men recover faster and have less incontinence afterward. About 40 men will be split into two groups: one gets standard car…
Phase: NA • Sponsor: University of Calgary • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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Can freezing nerves replace opioids for joint replacement waitlist pain?
Symptom relief Not yet recruitingThis study tests a pain relief method called cryoneurolysis, which uses cold to temporarily stop nerves from sending pain signals. It is for 30 adults waiting for hip or knee replacement who currently take daily opioids. The goal is to see if this approach can lower pain and redu…
Phase: NA • Sponsor: University of Calgary • Aim: Symptom relief
Last updated May 12, 2026 13:40 UTC
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Shocking away migraines? new electrical ear treatment tested
Symptom relief Not yet recruitingThis study tests a new, drug-free treatment for vestibular migraine, a condition causing repeated dizziness and headaches. Fifty adults will receive either real or placebo electrical stimulation behind the ears over two weeks. The goal is to see if the treatment is safe, comforta…
Phase: NA • Sponsor: University of Calgary • Aim: Symptom relief
Last updated May 11, 2026 20:39 UTC
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Could magnetic pulses tame ADHD? new study explores Drug-Free option
Symptom relief Not yet recruitingThis study tests if a non-invasive brain stimulation technique called theta burst rTMS can reduce ADHD symptoms like poor attention and hyperactivity in children aged 9-15. Researchers will measure changes in attention and quality of life. The goal is to find an alternative to st…
Phase: NA • Sponsor: University of Calgary • Aim: Symptom relief
Last updated May 06, 2026 16:13 UTC
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MRI heart monitoring gets a signal boost
Knowledge-focused Not yet recruitingThis study aims to improve the quality of ECG recordings taken during cardiac MRI scans. The magnetic field of the MRI can distort the ECG signal, making it harder to monitor the heart. Researchers will test ways to reduce this distortion in 2,500 adult patients referred for a ca…
Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated May 17, 2026 01:02 UTC
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Teen depression linked to monthly hormone shifts?
Knowledge-focused Not yet recruitingThis observational study looks at whether some teen girls with depression are sensitive to natural changes in estrogen and progesterone during their menstrual cycle. About 94 participants will track their hormone levels at home and answer daily mental health surveys for 90 days. …
Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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THC study aims to uncover Dose-Dependent effects on mind and body
Knowledge-focused Not yet recruitingThis study looks at how different amounts of oral THC (the active ingredient in cannabis) affect mood, heart rate, and drug feelings in healthy adults who have used cannabis before. Twenty-four participants will attend four visits, each time receiving a different dose or a placeb…
Phase: PHASE1 • Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Scientists to test if blocking the psychedelic 'Trip' kills the benefits
Knowledge-focused Not yet recruitingThis study looks at whether the intense, subjective experience (the 'trip') caused by psilocybin, the active ingredient in magic mushrooms, is necessary for its positive after-effects. Researchers will give 128 healthy adults psilocybin along with either a placebo or risperidone,…
Phase: PHASE2 • Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC
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Timing of stroke rehab could be key to better recovery
Knowledge-focused Not yet recruitingThis study looks at whether waiting until day 3 after a stroke to start physical therapy is better for patients with persistent artery blockages. Researchers will test if delayed mobilization is safe and helps reduce brain damage and improve recovery. The study involves 50 adults…
Phase: NA • Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated May 04, 2026 16:19 UTC