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Could magnetic pulses ease MS depression and fatigue?

NCT ID NCT07562074

Not yet recruiting Symptom relief Sponsor: University of Calgary Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether repetitive transcranial magnetic stimulation (rTMS) is safe and helpful for depression and fatigue in adults with multiple sclerosis (MS). About 20 participants will receive daily rTMS sessions for 5 days, with assessments before, after, and at a 4-week follow-up. The goal is to see if this non-invasive brain stimulation can improve mood, fatigue, and thinking in people with MS who haven't responded to standard treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS)
What this could lead to
If it works, this could point toward a new, non-invasive treatment option for depression and fatigue in people with multiple sclerosis.
What could go wrong
This is a very early, small pilot study with only 20 participants and no control group. The results may not apply to all MS patients, and safety in this population is still being tested.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression Fatigue major depressive disorder multiple sclerosis primary progressive multiple sclerosis relapsing-remitting multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION - MAJOR DEPRESSIVE DISORDER FATIGUE MULTIPLE SCLEROSIS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Foothills Medical Centre

    Calgary, Alberta, T2N 2T9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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