University Of Calgary

This study looks at whether a step-by-step care plan (called TheraPPP) helps patients with severe breathing failure (ARDS) survive and spend less time on a ventilator. The plan includes proven treatments like protective ventilation, paralysis, and prone positioning. About 20,000 …

This study tests whether a transition coordinator can help 324 youth aged 17–18 with type 1 diabetes successfully move from pediatric to adult diabetes care. Participants get extra support before, during, and after the switch. Researchers will compare them to a group that didn't …

This study tests a new microwave scanner that measures the electrical properties of breast tissue. Researchers will compare these scans to standard mammograms and ultrasounds in 100 women who need follow-up breast imaging. The goal is to see if microwave imaging can help detect b…

This study is testing a new device called Gastric Alimetry that records the stomach's electrical activity through electrodes placed on the belly. Researchers want to see if it can reliably detect abnormal stomach rhythms in people with conditions like gastroparesis and functional…

This study involves 60 young people at high risk for psychosis. They receive a stepped series of psychological treatments, starting with the least intensive options like group support, and moving to more intensive therapy if needed. The goal is to prevent the development of psych…

This study tests whether sending a short, encouraging letter from a pharmacist can motivate more adults to get their flu and travel vaccines. Researchers will track vaccination rates and also check if vaccinated people have fewer strokes in the following six months. About 20,000 …

This study tests whether adding a non-invasive brain stimulation technique called rTMS to a three-week intensive pain rehabilitation program can help youth aged 10-18 with severe chronic pain. The goal is to see if the stimulation can reduce pain and improve daily function, mood,…

This study looks at the cost and benefits of a two-week day camp for children with mild to moderate arm weakness (hemiparesis) from cerebral palsy or brain injury. In the first week, children wear a constraint on their stronger arm to encourage use of the weaker arm, followed by …

This study planned to test whether a lidocaine nerve block (SPG block) could reduce anxiety in adults at electronic dance music festivals, compared to a saline placebo. The trial was withdrawn before enrolling any participants, so no data were collected. The approach was experime…

This study tests whether adding group weight-loss classes to standard cardiac rehabilitation helps people with atrial fibrillation and obesity lose at least 10% of their body weight. About 120 adults will take part, with half getting the extra classes. The goal is to see if this …

This study tests whether a procedure called genicular radiofrequency ablation can safely reduce persistent knee pain in people who still hurt more than a year after total knee replacement. The procedure uses heat to temporarily calm specific nerves around the knee. Half of the 44…

This study looks at how two parts of cannabis, THC and CBD, affect thinking and bladder symptoms in people with Multiple Sclerosis (MS). Thirty adults with MS will take either THC or CBD oil for 15 weeks and complete tests and questionnaires. The goal is to see if one compound he…

This study looks at whether a bundle of tools—like education for doctors, feedback reports, and patient infographics—can cut down on repetitive, low-value lab tests in hospitals. Over 250,000 patients across 14 hospitals in Alberta are included. The goal is to reduce patient disc…

This study is testing whether a simple saliva test can help doctors choose the right psychiatric medications for children and teens aged 6 to 24. The test looks at the child's DNA to predict how they might respond to different drugs. Researchers hope this will lead to fewer side …

This study looks at whether adjusting tube feeding based on total daily volume, rather than a fixed hourly rate, helps critically ill children get more of the nutrition they need. The trial involves 20 children in the pediatric ICU and aims to see if this approach is practical fo…

This study tests a simple rule to see if a bile leak stent can be safely removed using a less invasive gastroscopy instead of a repeat ERCP. The rule uses four easy-to-check factors, like normal blood test results and the type of leak. If validated, this approach could reduce rad…