Brain zaps may help teens with chronic pain get more from rehab

NCT ID NCT04561401

Ongoing Symptom relief Sponsor: University of Calgary Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a non-invasive brain stimulation technique called rTMS to a three-week intensive pain rehabilitation program can help youth aged 10-18 with severe chronic pain. The goal is to see if the stimulation can reduce pain and improve daily function, mood, and brain activity. It's a small early trial with 25 participants, so results will be preliminary.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repeated transcranial magnetic stimulation (rTMS)
What this could lead to: If it works, this could point toward a new way to ease chronic pain and improve daily life for youth who haven't gotten relief from other treatments.
What could go wrong: This is a very small, early study with only 25 participants and no control group. The results may not apply to all youth with chronic pain, and the benefits might be modest.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC PAIN

Contacts and locations

Locations

University of Calgary

Calgary, Alberta, T3B 6A8, Canada

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