Could a gut makeover ease ADHD? a trial tests FMT in teens
NCT ID NCT07756255
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This phase 2 trial explores whether fecal microbiota transplantation (FMT) is safe, tolerable, and practical for adolescents aged 13–17 with ADHD. Participants receive oral FMT capsules after bowel prep, alongside antibiotics, to see if changing gut bacteria can influence ADHD symptoms. The study focuses on feasibility, safety, and tolerability, not yet on whether it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Fecal microbiota transplant (FMT) capsules, given with antibiotics (nitazoxanide and vancomycin) and bowel prep
- What this could lead to
- If FMT proves safe and feasible, it could open a new avenue for managing ADHD symptoms by altering the gut microbiome.
- What could go wrong
- This is an early-phase trial focused on safety and feasibility, not proof of effectiveness. FMT carries risks like infection or gastrointestinal discomfort, and results may not generalize.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Calgary
Calgary, Alberta, T2M 1R5, Canada
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