University Hospital, Brest
Clinical trials sponsored by University Hospital, Brest, explained in plain language.
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Breathing mask before surgery could cut complications in half
Disease control CompletedThis study tested whether using a special breathing mask for at least 7 days before lung cancer surgery could reduce serious complications after the operation. It focused on patients at higher risk due to existing breathing problems, obesity, or heart failure. The goal was to see…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New knee repair technique tested against standard surgery
Disease control CompletedThis study compared two surgical methods to repair damaged knee cartilage in adults. It tested a newer cell-transplant technique against a standard cartilage-plug procedure. Researchers followed 58 patients for two years to see which method better improved knee function and pain.
Phase: PHASE3 • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Before or after? insulin timing study aims to simplify diabetes management
Disease control CompletedThis study compared whether taking insulin right before or right after meals works better for controlling blood sugar in people with type 1 diabetes who use insulin pumps. Researchers followed 22 adults with type 1 diabetes to see which timing led to more stable blood sugar level…
Phase: PHASE3 • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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New fluid strategy aims to protect organs in deadly shock
Disease control CompletedThis study tested whether a personalized plan for giving fluids to patients with septic shock could reduce organ damage. Doctors compared a new method using small 'mini-challenges' of fluid to see how a patient's body responds, against the usual standard care. The goal was to fin…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated Mar 09, 2026 14:26 UTC
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Hidden danger: researchers hunt for silent blood clots in COPD patients
Diagnosis CompletedThis study aimed to find out how often people hospitalized for a sudden worsening of COPD (chronic obstructive pulmonary disease) also have a dangerous blood clot in their lungs. Researchers tested 750 patients using a standard set of scans and blood tests to look for these clots…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Apr 01, 2026 14:42 UTC
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Faster, clearer scan for deadly lung clots?
Diagnosis CompletedThis study tested a new type of PET scan to see if it could accurately diagnose pulmonary embolism (PE), which is a dangerous blood clot in the lungs. It compared the new scan to the current standard CT scan in 100 patients suspected of having a first-time clot. The goal was to s…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Mar 31, 2026 12:10 UTC
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One scan, two answers: new test aims to sharpen detection of deadly lung clots
Diagnosis CompletedThis study tested a new type of CT scan that aims to improve the diagnosis of pulmonary embolism (a dangerous blood clot in the lungs). Researchers compared this new scan, which can show both the clot and how it affects blood flow, against a standard older scan method. The goal w…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Mar 30, 2026 14:33 UTC
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New tool aims to help doctors spot hidden depression
Diagnosis CompletedThis study tested a French version of a questionnaire called HSCL-25 to see if it helps general practitioners diagnose depression more accurately. Over 1,100 adult patients visiting their primary care doctor participated. Researchers compared the results of this new questionnaire…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Mar 30, 2026 14:28 UTC
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Can a simple text stop a suicide? caregivers test new alert system
Prevention CompletedThis study tested whether sending text messages could help caregivers monitor adults who recently attempted suicide, aiming to prevent another attempt. Researchers enrolled 15 patients and their caregivers to see if this text-based check-in system was practical and acceptable. Th…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Prevention
Last updated Apr 01, 2026 14:40 UTC
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Light beams aim to stop Post-LASIK dry eye before it starts
Prevention CompletedThis study tested whether two types of light therapy given before laser eye surgery (like LASIK) could prevent dry eye, a common and uncomfortable side effect. Researchers enrolled 62 patients scheduled for surgery and randomly assigned some to receive the light treatments. They …
Phase: NA • Sponsor: University Hospital, Brest • Aim: Prevention
Last updated Mar 30, 2026 14:34 UTC
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Pumping legs to stop killer clots: a safer option for ICU patients
Prevention CompletedThis study tested whether adding leg compression sleeves to standard compression stockings was better at preventing blood clots than stockings alone. It focused on intensive care unit (ICU) patients who were at high risk of serious bleeding, meaning they could not safely take sta…
Phase: PHASE3 • Sponsor: University Hospital, Brest • Aim: Prevention
Last updated Mar 27, 2026 12:38 UTC
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New breathing exercises tested to help COPD patients breathe easier
Symptom relief CompletedThis study tested whether adding specific breathing muscle training to standard pulmonary rehabilitation helps reduce shortness of breath in people with COPD more than rehabilitation alone. Researchers worked with 38 hospitalized COPD patients who had normal breathing muscle stre…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Mother's milk vs sweet syrup: which soothes babies better during shots?
Symptom relief CompletedThis study tested whether breastfeeding or a sugar solution works better to reduce pain in newborns during medical procedures like injections. Researchers enrolled 114 healthy, full-term breastfed babies and measured brain activity changes during the procedures. The goal was to f…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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New hope for relieving debilitating itch in blood cancer patients
Symptom relief CompletedThis study tested whether the drug aprepitant works better than hydroxyzine to relieve severe itching triggered by water in people with certain blood cancers. 63 adult patients who experienced this persistent, bothersome itch participated. They took one of the two pills for 14 da…
Phase: PHASE3 • Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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Pill tested to stop embarrassing sweat
Symptom relief CompletedThis study tested whether a medication called oxybutynin could effectively reduce excessive sweating (hyperhidrosis) in adults. 62 participants with moderate to severe sweating were randomly assigned to receive either the real medication or a placebo pill. Researchers measured ch…
Phase: PHASE3 • Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Zap vs. pedal: can electrical muscle stimulation help COPD patients breathe easier?
Symptom relief CompletedThis study tested two different ways to strengthen leg muscles as part of a standard 3-4 week pulmonary rehabilitation program for people with severe COPD. Researchers compared using a special electrical stimulation device on the thigh muscles versus using a stationary exercise b…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated Mar 30, 2026 14:27 UTC
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Gentle light tested to soothe sensitive skin
Symptom relief CompletedThis study tested whether LED light therapy could help reduce the discomfort of sensitive skin. Thirty adults with sensitive skin received light treatments over eight weeks. Researchers measured changes in skin sensitivity, itching, and pain while checking for any side effects.
Phase: NA • Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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New ultrasound device aims to improve hip replacement planning
Knowledge-focused CompletedThis study tested a portable ultrasound device to see how reliably it could measure pelvic tilt (the angle of the pelvis). Researchers measured 3 healthy volunteers and 30 patients getting hip replacements to see if the device gave consistent readings between different operators.…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Could a simple bladder trick make IUD insertion less painful?
Knowledge-focused CompletedThis study aims to understand how a full or empty bladder changes the angle of the uterus in women who have given birth. Researchers measured 200 women to see if bladder fullness makes it easier for doctors to insert an IUD. The goal is to gather knowledge that could lead to less…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Could special diabetic shoes increase fall risk?
Knowledge-focused CompletedThis study aimed to find out if a specific type of shoe, called a 'rocker sole' shoe, affects balance in people with diabetes-related nerve damage (neuropathy). Researchers compared these special shoes to standard shoes in 25 participants. They measured how much a person's body s…
Phase: PHASE4 • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Doctors test if weight loss surgery changes how blood thinners work
Knowledge-focused CompletedThis study aimed to understand how weight loss surgery and severe obesity affect how the body processes a common blood thinner called rivaroxaban. Researchers gave the medication to 67 people across four groups: severely obese individuals, those who had gastric bypass surgery, th…
Phase: PHASE1 • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:27 UTC
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Scientists measure young adults to decode shoulder test scores
Knowledge-focused CompletedThis study aimed to understand how a person's body measurements and physical activity level affect their score on a common shoulder stability test. Researchers tested 82 healthy young adults aged 18-25. They performed a specific push-up style test and answered activity questionna…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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One walk or two? study tests best way to measure COPD recovery
Knowledge-focused CompletedThis study looked at whether performing two walking tests, instead of the usual one, at the end of a COPD rehabilitation program gives a more accurate picture of a patient's true abilities. Researchers compared the distance walked on a first and second test by 176 patients with m…
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:37 UTC
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Doctors map healthy nerves to spot problems sooner
Knowledge-focused CompletedThis study aimed to establish what a normal ulnar nerve looks like on ultrasound at the elbow in people without nerve problems. Researchers measured the nerve size in 50 healthy volunteers to create a reliable baseline for comparison. The goal is to help doctors better identify a…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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Researchers test simple stepper as new way to track COPD rehab progress
Knowledge-focused CompletedThis study tested whether a 6-minute stepper test, which can be done in a regular room, could effectively measure changes in exercise ability for people with COPD during a 3-week pulmonary rehabilitation program. Researchers compared it to the standard walking test that requires …
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Mar 12, 2026 13:51 UTC
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Brain's balance control may hold key to preventing devastating knee injuries in athletes
Knowledge-focused CompletedThis study aimed to understand if how the brain processes balance signals from the legs influences the risk of a serious knee ligament tear during sports. Researchers measured the movements of 41 young, competitive handball players while they performed jumps and quick direction c…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Mar 06, 2026 15:37 UTC