Can a leg pump prevent clots in Bleeding-Prone patients?

NCT ID NCT00740844

Completed Prevention Sponsor: University Hospital, Brest Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding a leg compression device to elastic stockings reduces blood clots in intensive care patients at high risk of bleeding. Over 400 patients were randomly assigned to receive either the device plus stockings or stockings alone. The main goal was to see if the combination lowered the number of blood clots in the legs or lungs by day 6.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: intermittent pneumatic compression device
What this could lead to: If it works, this could provide a safer way to prevent dangerous blood clots in patients who cannot take blood thinners.
What could go wrong: This is a completed Phase 3 trial, but results may not apply to all hospital settings. The device may cause discomfort or skin issues, and the benefit over stockings alone may be small.

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Conditions

The condition(s) this trial relates to.

Hemorrhage venous thromboembolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMORRHAGE HIGH BLEEDING RISK

Contacts and locations

Locations

HIA Clermont-Tonnerre

Brest, 29 000, France
Intensive Care Unit

Limoges, France
Medical Intensive Care Unit

Brest, France
Medical Intensive Care Unit

Lille, France
Medical Intensive Care Unit

Nantes, France
Medical Intensive Care Unit

Paris, France
Medical intensive care unit

Angoulême, France
Medical intensive care unit

Orléans, France
Medical intensive care unit

Poitiers, France
Medical intensive care unit

Tours, France

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