Massive trial tests cheap drug to stop Post-C-Section hemorrhage
NCT ID NCT03364491
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This large study tested whether giving tranexamic acid (TXA) during C-sections can prevent severe bleeding. Over 11,000 women received either TXA or a placebo right after delivery. The goal was to see if TXA reduces the need for blood transfusions or death. Results could change how doctors manage bleeding risks in cesarean births.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tranexamic acid (TXA)
What this could lead to
If effective, this could make C-sections safer by reducing the need for blood transfusions and preventing severe bleeding.
What could go wrong
This trial is complete, but results may not apply to all women. TXA carries a small risk of blood clots, which was monitored closely.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEMORRHAGE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Brown University
Providence, Rhode Island, 02905, United States
-
Case Western Reserve-MetroHealth
Cleveland, Ohio, 44109, United States
-
Columbia University
New York, New York, 10032, United States
-
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
-
Magee Women's Hospital of UPMC
Pittsburgh, Pennsylvania, 15213, United States
-
Northwestern University-Prentice Hospital
Chicago, Illinois, 60611, United States
-
Ohio State University Hospital
Columbus, Ohio, 43210, United States
-
University of Alabama - Birmingham
Birmingham, Alabama, 35233, United States
-
University of North Carolina - Chapel Hill
Chapel Hill, North Carolina, 27599, United States
-
University of Texas - Houston
Houston, Texas, 77030, United States
-
University of Texas Medical Branch
Galveston, Texas, 77555, United States
-
University of Utah Medical Center
Salt Lake City, Utah, 84132, United States