New inhaler could ease tooth pain in minutes
NCT ID NCT06495372
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether methoxyflurane (Penthrox®), a painkiller inhaled through a handheld device, can quickly reduce moderate to severe dental pain in adults. 190 participants in a dental emergency department received either methoxyflurane or a placebo alongside standard care. The main goal was to see if pain dropped within 15 minutes, offering a fast relief option while waiting for a dentist.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- methoxyflurane (Penthrox®)
- What this could lead to
- If it works, this could provide a fast, effective painkiller for people with severe dental pain while they wait for a dentist.
- What could go wrong
- This is a completed Phase 3 trial, but the results are not yet published. Methoxyflurane may cause side effects like drowsiness or nausea, and it may not work better than placebo.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Brest
Brest, 29200, France
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Other studies related to the condition(s) this trial covers.