University Hospital, Brest

This phase II trial tested an experimental drug called roscovitine in 36 adults with cystic fibrosis who have a common genetic mutation and a chronic lung infection. The goal was to check the safety of different doses given in short cycles. The study was terminated early, so its …

This study tested whether a special type of PET/CT scan, called PSMA PET/CT, can better detect if prostate cancer has spread to nearby lymph nodes before surgery. The scan uses a radioactive tracer that sticks to prostate cancer cells, making them visible. The goal was to help do…

This study tested whether offering a home urine test for human papillomavirus (HPV) could encourage more women to get screened for cervical cancer. The trial targeted women aged 30–65 in Brittany, France, who had not responded to an initial invitation for a Pap smear. Participant…

This study tested a smartphone app called 'Bouge' to see if it could help women with non-metastatic breast cancer increase their daily steps while on weekly Taxol chemotherapy. The goal was to add 3,000 steps per day over 90 days. Only 23 people enrolled, and the trial was stoppe…

This study aimed to understand how well patients tolerate biopsies for autoimmune diseases and whether they feel properly informed. It planned to enroll 505 people but was terminated early. The results may help improve patient experience with these common procedures.

This study aimed to track how different immune cells (lymphocytes) change over time in ICU patients with severe infections or injuries. Researchers hoped to better understand 'immunoparalysis,' a state where the immune system becomes weak after severe inflammation. The study was …

This study aimed to see how total hip replacement changes the way the pelvic bone moves during daily activities like sitting and standing. Researchers used an ultrasound device to measure pelvic tilt in 15 people with hip arthritis before and after surgery. The study was terminat…

This study aimed to measure how eye volume changes (a sign of pressure fluctuation) before and after cataract surgery in patients with exfoliative glaucoma, a type of glaucoma common in Brittany. Only 6 adults were enrolled before the study was terminated. The goal was to see if …

This study aimed to find out how common non-tuberculous mycobacteria (NTM) infections are in people with cystic fibrosis in France. Researchers collected sputum and blood samples from 848 participants to test for NTM using culture and a new blood test. The study was terminated ea…

This study aimed to create a library of biological samples and clinical data from 250 women with unexplained infertility or low ovarian reserve. Researchers collected blood, DNA, vaginal swabs, and fluid from egg retrieval to help future studies find markers that predict pregnanc…

This study filmed consultations between dermatologists and infants under 6 months old with atopic dermatitis (eczema). Researchers analyzed the videos to identify specific behaviors that might indicate discomfort, since standard itch assessment scales don't work for babies this y…

This study looked at 91 premature babies to see if measuring heart rate and skin sweat can help detect pain as well as a standard behavioral scale. Researchers recorded these body signals during routine medical procedures. The goal was to find a more objective way to assess pain …