Smart fluid dosing could save organs in septic shock patients

NCT ID NCT03461900

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 25 times

Summary

This study tested a personalized approach to giving fluids to people with septic shock, a life-threatening condition where organs start to fail. Instead of a one-size-fits-all method, doctors used a 'mini-fluid challenge' to tailor fluid amounts to each patient's needs. The goal was to reduce organ damage, measured by a score called SOFA. The trial included 535 adults in intensive care units and compared this tailored method to usual care.

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Contacts and locations

Locations

  • Angers university hospital

    Angers, France

  • Besançon university hospital

    Besançon, France

  • Brest university hospital

    Brest, 29200, France

  • Brest university hospital

    Brest, France

  • Chartres Hospital

    Chartres, 28000, France

  • Clermont Ferrand university hospital

    Clermont-Ferrand, France

  • George Pompidou university hospital (APHP)

    Paris, France

  • Hôpital privé de l'ouest parisen

    Trappes, 78190, France

  • Kremlin Bicêtre university hospital (APHP)

    Paris, France

  • Le Mans hospital

    Le Mans, France

  • Marseille university horpital

    Marseille, France

  • Morlaix hospital

    Morlaix, France

  • Nantes university hospital

    Nantes, France

  • Nîmes university hospital

    Nîmes, 30029, France

  • Poitiers university hospital

    Poitiers, France

  • Rouen university hospital

    Rouen, France

  • Toulon hospital

    Toulon, France

  • Tours university hospital

    Tours, France

Conditions

Explore the condition pages connected to this study.