Northwell Health

This study tests whether lisinopril, a blood pressure drug that works in the brain, can improve memory and concentration problems in people with lupus. About 36 adults with lupus will take either lisinopril or another similar drug for 12 months. Researchers will measure changes i…

This study tests a website tool called WeCareToFeedDysphagia designed to reduce stress and burden for people caring for older adults with Alzheimer's or related dementias who also have trouble swallowing. About 800 caregivers will either get access to the tool or not, and all wil…

This study tests whether a device called Urolift, which lifts the prostate away from the urethra, can reduce urinary problems like frequent urination and pain after radiation therapy for prostate cancer. About 20 men with both prostate cancer and an enlarged prostate (BPH) will r…

This study tests whether personalized text messages can help 100 caregivers of people with Alzheimer's disease develop a habit of walking at least 250 steps each hour. The goal is to see if at least half of the participants can build this healthy habit over 12 weeks. The approach…

This study tests whether injecting Botox into the bladder muscle can reduce urine leakage in women with stress urinary incontinence. About 20 women who have not improved with other treatments will receive the injection and be monitored for changes in leakage and side effects. The…

This study tests if a device called PureWick can help women aged 50 and older who wake up to urinate at least twice a night. The goal is to reduce the number of nighttime bathroom trips and lower the risk of falls. Forty participants will use the device and be followed for three …

This study tests whether personalized text messages can help 100 caregivers of people with Alzheimer's disease develop a daily walking habit. Caregivers who are not very active will receive texts over 12 weeks to encourage them to walk at least 1,000 steps in a one-hour period ea…

This study planned to test whether giving a mix of cold saline, minocycline, and magnesium directly to the brain during a stroke procedure could protect brain tissue and improve recovery. It was designed for adults aged 18-90 having a severe stroke due to a large blockage. Howeve…

This small pilot study tests whether a non-invasive device that gently stimulates a nerve in the ear can affect the heart's electrical system. Ten adults already scheduled for a heart procedure will receive the stimulation while doctors measure changes in heart timing and rhythm.…

This observational study looks at how the immune system responds to flu and COVID-19 vaccines in people with chronic spinal cord injuries compared to healthy individuals. Researchers will measure antibody levels and gene activity in blood samples to see if injury level or severit…

This study follows 32 people with Parkinson's disease to see if those with a specific gene change (GBA mutation) have faster changes in brain activity over time. Participants will have brain scans and tests of movement and thinking. The goal is to understand how genes influence t…