Northwell Health

This phase 2 trial is testing whether giving two drugs—Zanzalintinib and Retifanlimab—before surgery can help patients with early-stage colon cancer. The study enrolls adults aged 18 to 80 with a type of colon cancer called pMMR that can be removed surgically. Participants receiv…

This trial investigates whether adding bortezomib and sitagliptin to standard post-transplant cyclophosphamide can prevent graft-versus-host disease (GvHD) in adults with blood cancers receiving a stem cell transplant. Participants receive the drug combination after transplant, w…

This study explores whether an additional CT scan of the heart, taken right after a standard scan for lung clots, can effectively detect blood clots in the left atrial appendage (LAA) in people with atrial fibrillation. Currently, detecting these clots requires a more involved pr…

This pilot study tests whether a structured discharge summary template and a chat-based educational messaging program can improve care transitions for adults leaving the hospital after acute kidney injury (AKI). Researchers will enroll 160 adults with moderate-to-severe AKI and c…

This pilot study will use advanced MRI scans to create detailed maps of brain connections in 10 people who have had a stroke in the middle cerebral artery. The goal is to understand how stroke disrupts the brain's network and whether these maps can help predict recovery and guide…

This study looks at how receiving positive urine culture results impacts stress levels and bladder symptoms in women with recurrent urinary tract infections (UTIs). Researchers will follow 170 women, including those with interstitial cystitis or bladder pain syndrome, using quest…