Northwell Health

This trial investigates whether famotidine, the active ingredient in Pepcid, can help relieve COVID-19 symptoms in adults who are not sick enough to be hospitalized. Participants receive either famotidine or a placebo, along with standard care, and report their symptoms remotely.…

This study tested a new surgical technique in 12 patients with newly diagnosed glioblastoma, an aggressive brain cancer. Surgeons placed a tissue flap from the scalp into the brain tumor cavity to bypass the blood-brain barrier, which normally blocks many treatments. The main goa…

This pilot study tested whether tailored text messages could help head and neck cancer survivors stop drinking alcohol, which is a major risk factor for cancer recurrence. 126 survivors from a hospital and a VA medical center were randomly assigned to receive either the text mess…

This study tested whether daily text messages with specific behavior change techniques could help sedentary adults at risk for cardiovascular disease walk an extra 1,000 steps per day. Over 600 participants received messages focused on goal setting, action planning, self-monitori…

This study tested a new approach that combines a minimally invasive spine-stabilizing procedure (kyphoplasty) with a single dose of targeted radiation given during surgery. The goal was to see if this combination could better control pain from cancer that has spread to the spine.…

This study tested whether changing how fast pressure increases during hyperbaric oxygen therapy (HBOT) can lower the chance of ear pain and injury. Over 1,500 people receiving HBOT were randomly assigned to one of two compression schedules. The goal was to see if a non-linear (sl…

This pilot study tested a website tool called WeCareToFeedDysphagia designed to reduce feelings of burden in caregivers of people with Alzheimer's or related dementias who also have trouble swallowing. Eighty caregivers were split into two groups: one got access to the tool plus …

This completed trial tested whether personalized text messages could help 100 caregivers of people with Alzheimer's disease build a habit of walking at least 250 steps each hour. The 12-week program used goal setting, action planning, self-monitoring, and prompts to encourage reg…

This study tested whether personalized text messages could help 100 caregivers of people with Alzheimer's disease develop a regular walking habit. Over 12 weeks, participants received texts with goal-setting, action plans, and reminders to walk at least 1,000 steps in a set hour …

This study tested a non-invasive device that gently stimulates a nerve in the ear to reduce frequent premature ventricular contractions (PVCs), a type of heart palpitation. Sixty adults who could not take or did not benefit from standard heart medications participated. The goal w…

This study tested a web-based program called RELOAD-C designed to reduce loneliness in people caring for a family member or friend with Alzheimer's disease. The program uses short videos and online group discussions based on Meaning-Centered Psychotherapy to help caregivers find …

This study tested whether personalized 'N-of-1' trials—where each person tries different stress management techniques in a specific order—can reduce stress better than standard care. 212 adults with high stress tried mindfulness meditation, yoga, and brisk walking over several we…

This study tested a program to help bladder cancer patients and their caregivers prepare for and recover from bladder removal surgery. A nurse or health professional provided pre-surgery education and stoma care training, and patients got access to a recovery website with videos …

This completed Phase 2 trial tested whether a personalized mind-body program could improve sleep in 60 women aged 40–60 who work in healthcare and report short sleep. Participants tried 30-minute sessions of mindfulness, yoga, and guided walking in different orders over 12 weeks.…

This study tests a multi-component behavioral intervention to find the minimum number of weeks needed to help adults on statin therapy increase their daily walking by 2,000 steps. Participants wear a Fitbit to track steps and receive techniques like goal setting, action planning,…

This study tested whether a small ultrasound patch called FloPatch can help emergency doctors predict which sepsis patients will need intensive care. The device measures how well the heart responds to fluids. Researchers followed 134 patients to see if FloPatch readings could pre…

This completed study looked at whether a breathing treatment called Intrapulmonary Percussive Ventilation (IPV) can improve lung stiffness (compliance) in critically ill children who are on breathing machines. Researchers measured lung function before and after one IPV session in…

This study tested a training program for emergency department staff to better detect delirium—a sudden confusion—in older adults. Researchers trained nurses and doctors at three hospitals and checked if detection improved. About 3,000 patients were involved. The goal was to see i…

This study tested a training program to help emergency department nurses better detect delirium in older adults. Delirium, a sudden confusion, affects up to 20% of older ER patients and is often missed. The program trained nurse champions through workshops and telehealth sessions…