Can a digestive enzyme device help pancreatitis patients tolerate tube feeds?

NCT ID NCT07583342

ENROLLING_BY_INVITATION Symptom relief Sponsor: Northwell Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether RELiZORB, a cartridge containing fat-digesting enzymes, can help adults with moderate to severe acute pancreatitis tolerate tube feeding better. Fifteen participants in the ICU will receive the device and be monitored for how much nutrition they can take in. The goal is to see if more calories can be delivered compared to before using the device.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: RELiZORB digestive enzyme cartridge (immobilized lipase)
What this could lead to: If it works, this could offer a way to improve nutrition delivery in hospitalized pancreatitis patients who struggle with tube feeding.
What could go wrong: This is a very small, early-phase study with only 15 participants, so results may not apply broadly. The device may not significantly improve feeding tolerance.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute pancreatitis pancreatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE PANCREATITIS (AP) ENHANCING ENTERAL NUTRITION TOLERANCE

Contacts and locations

Locations

Lenox Hill Hospital

Manhattan, New York, 10075, United States
Long Island Jewish Medical Center

New Hyde Park, New York, 11040, United States
North Shore University Hospital

Manhasset, New York, 11030, United States
South Shore University Hospital

Bay Shore, New York, 11706, United States
Staten Island University Hospital

Staten Island, New York, 10305, United States

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