Stroke neuroprotection trial pulled before it started
NCT ID NCT05032781
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This was a very early (Phase 1) study that planned to give a mixture of cold saline, minocycline, and magnesium directly into the brain's arteries right after a stroke procedure to reopen blocked vessels. The goal was to see if this cocktail could safely protect brain tissue and improve recovery. However, the trial was withdrawn before enrolling any participants, so no results are available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cold saline, minocycline, and magnesium sulfate
- What this could lead to
- If this approach had been tested and worked, it could point toward a way to protect brain tissue during stroke treatment, potentially reducing long-term disability.
- What could go wrong
- This trial was withdrawn before any participants were enrolled, so no data is available. Even if tested, it was an early Phase 1 safety study, and the combination might not have improved outcomes or could have caused harm like bleeding.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
North Shore University Hospital
Manhasset, New York, 11030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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