Stroke neuroprotection trial pulled before it started
NCT ID NCT05032781
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This was a very early (Phase 1) study that planned to give a mixture of cold saline, minocycline, and magnesium directly into the brain's arteries right after a stroke procedure to reopen blocked vessels. The goal was to see if this cocktail could safely protect brain tissue and improve recovery. However, the trial was withdrawn before enrolling any participants, so no results are available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cold saline, minocycline, and magnesium sulfate
What this could lead to
If this approach had been tested and worked, it could point toward a way to protect brain tissue during stroke treatment, potentially reducing long-term disability.
What could go wrong
This trial was withdrawn before any participants were enrolled, so no data is available. Even if tested, it was an early Phase 1 safety study, and the combination might not have improved outcomes or could have caused harm like bleeding.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for STROKE, ISCHEMIC are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
North Shore University Hospital
Manhasset, New York, 11030, United States