Could a 'robotic cough' stop deadly pneumonia in ICU patients?

NCT ID NCT06113939

First seen Jun 29, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This pilot study tests two non-invasive methods to keep the airways clear in adults who are unconscious or severely ill and need a breathing tube. One method uses a special tube with continuous low-pressure suction, and the other delivers a programmed 'artificial cough' through the ventilator. The goal is to see if these approaches can prevent early pneumonia better than the current standard of care, which involves antibiotics or manual suctioning. The study includes 60 patients with conditions like severe trauma, stroke, or cardiac arrest, and follows them for 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
airway clearance device
What this could lead to
If successful, this could point toward safer, non-invasive ways to prevent lung infections in intensive care patients, reducing antibiotic use and complications.
What could go wrong
This is a small pilot study (60 patients), so results may not be definitive. The non-invasive devices might not work as well as current methods, and any approach could still fail to prevent infection.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Clinico San Carlos

    Madrid, Madrid, 28040, Spain

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Other studies related to the condition(s) this trial covers.