Mansoura University

This study tests three methods to rebuild the small triangle of gum between teeth (papilla) that has been lost. The methods are: injecting hyaluronic acid (a filler), injecting a special blood product (ALB-PRF) that lasts longer, or a small surgery. The goal is to see which works…

This study compares two types of fixed braces—a 3D-printed twin block and a MARA appliance—to see which works better for correcting a common jaw problem in preteens (Class II malocclusion, where the lower jaw is too far back). About 60 children will be randomly assigned to one of…

This study tests whether two diabetes drugs (dapagliflozin and empagliflozin) can help adults with nephrotic syndrome, a kidney condition that causes protein leakage and swelling. About 75 participants will receive either one of these drugs plus standard care, or standard care al…

This study tests a custom 3D-printed device that uses small screws anchored to the bone to widen the upper jaw in young adults aged 18-30. The goal is to see how well it opens the mid-palatal suture and affects tooth position and bone thickness. Sixteen participants will wear the…

This study looks at three types of tooth-colored onlays (custom-made fillings) for back teeth with deep cavities that go below the gum line. Researchers will first build up the cavity edge, then place three different onlays in each of 18 adult patients. They will check the fillin…

This study tests whether a stellate ganglion block (an injection near nerves in the neck) given before mastectomy can prevent depression and chronic pain afterward. About 140 women with breast cancer will receive either the block or a placebo. The goal is to see if this simple pr…

This study compares two once-daily pills—tadalafil and solifenacin—to see which one works better for women with overactive bladder (OAB). OAB causes sudden urges to urinate, frequent bathroom trips, and sometimes leakage. About 480 women aged 18 to 75 with OAB symptoms for at lea…

This study tests whether taking a daily low-dose ED pill plus an extra on-demand pill works better than the on-demand pill alone for men who don't get good results from standard ED drugs. About 500 men with long-term erectile dysfunction will take the combination or a placebo for…

This study tests three different methods of taking dental impressions to make 3D-printed false teeth for people with no teeth. Sixteen patients will try each set of teeth for three months to see which method helps them chew best and feels most comfortable. The goal is to find the…

This study looks at whether custom-made braces (Carriere Motion Appliance) work better than ready-made ones for teens aged 12-15 with a specific bite problem called Class II malocclusion. Researchers will measure how long treatment takes, changes in teeth and jaw, and how satisfi…

This study looks at whether numbing the upper and lower jaw nerves before surgery can lower pain and the need for extra pain medicine after jaw surgery. About 60 adults having planned jaw surgery will take part. The goal is to see if this nerve block helps control pain better tha…

This study tests whether injecting botulinum toxin (like Botox) into the surgical site can reduce scarring after cleft lip repair. About 32 people with mild to severe unilateral cleft lip will receive the injection during surgery. Researchers will measure scar width and use a sta…

This study tests if special pelvic floor exercises can reduce or stop the small urine leak some men experience after urinating. Researchers will compare targeted exercises to general exercises in 120 men aged 18 to 40 over 12 weeks. The goal is to see if these exercises improve s…

This study tests whether a combination of two drugs (mirabegron and solifenacin) works better than the standard drug (desmopressin) for children who wet the bed. About 120 children will take one of the treatments daily for 3 months. The goal is to see which approach reduces the n…

This study tests whether giving the painkiller ketorolac directly into the blood flow of a leg (while a tourniquet is on) can extend pain relief after lower limb orthopedic surgery. About 76 adults having elective leg surgery under spinal anesthesia will be randomly assigned to r…

This study tests whether low-intensity shockwave therapy can ease overactive bladder symptoms in women better than a daily pill. About 70 women will receive either weekly shockwave sessions for 8 weeks or a standard medication for 12 months. Researchers will track symptom changes…

This study looks at two different dental filling materials used for cavities near the gum line (class V restorations). Researchers want to see if one material or polishing method works better. About 25 adults with these cavities will be treated and followed for 2 years to check h…

This study looks at whether doctors can predict a condition called stridor (noisy, difficult breathing) after removing a breathing tube in patients who had jaw surgery. The researchers will measure the width of the airway using a special test before removing the tube. The goal is…

This study looks at how well the heart pumps blood during a C-section when using spinal anesthesia. Two drugs, norepinephrine and ephedrine, are compared to see which one keeps the heart function more stable. The study involves 200 healthy women with a full-term single baby who a…