Mansoura University
Clinical trials sponsored by Mansoura University, explained in plain language.
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Could a plant extract beat standard root canal treatments?
Disease control OngoingThis study tests whether oleanolic acid, a natural plant compound, works better than standard medicines (calcium hydroxide and Ledermix) when placed inside a root canal. The goal is to reduce bacteria and inflammation in teeth with infection. Thirty-six adults with infected singl…
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 16, 2026 22:04 UTC
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New study tests better implants for weak jawbones
Disease control OngoingThis study compares two types of dental implants (basal vs. compressive) in 14 people with severe jawbone loss. All implants are placed in the front of the lower jaw and immediately fitted with a bar-supported denture. Researchers will check gum health, bone levels, and implant s…
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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New tooth-shaped implant tested for better denture support
Disease control OngoingThis study compares a new bio-implant (shaped like a natural tooth root) to a standard screw-type implant for supporting partial dentures in people missing back teeth. Eight participants with specific jaw conditions received both types of implants. Researchers measured bone and g…
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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Braces vs. clear aligners: which is better for crowded teeth?
Disease control OngoingThis study compares two common orthodontic treatments—clear aligners and traditional braces—for adults with mild to moderate dental crowding. Researchers will measure changes in bone thickness and height around the teeth, as well as tooth movement and root shortening. The goal is…
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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New bone putty aims to boost dental implant success in front teeth
Disease control OngoingThis study looks at whether a bone graft putty added to dental implants helps bone and gum heal better after a tooth is removed. About 72 people with a damaged front tooth will get an implant with or without the putty. The goal is to see if the putty improves implant stability an…
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Digital brace could fix Kids' underbite without surgery
Disease control ENROLLING_BY_INVITATIONThis study tests a new digital brace (Digital Bonded Reverse Twin Block) for children aged 8-11 with a mild underbite. The brace is custom-made using digital scans and is bonded to the teeth to gently shift the jaw and improve the bite and facial profile. The study will measure c…
Phase: PHASE1 • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 08, 2026 13:10 UTC
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Gum graft showdown: which technique wins for dental implants?
Disease control OngoingThis study looks at two different ways to place gum tissue grafts during dental implant surgery. The goal is to find which method helps the gum heal better and reduces bone loss around the implant. Twenty healthy adults with good oral hygiene are taking part.
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 08, 2026 13:09 UTC
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Omega-3 tooth treatment shows promise for saving Kids' teeth
Disease control OngoingThis study tests whether placing omega-3 fatty acids inside a damaged tooth can help it regrow root length and dentin wall thickness. Twenty children and young adults (ages 6–28) with immature permanent teeth that have died (pulp necrosis) will receive either the omega-3 treatmen…
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 03, 2026 12:07 UTC
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Pig collagen patch may strengthen gums around implants
Disease control OngoingThis study tests whether a patch made from pig collagen can help improve the gum tissue around dental implants in 20 adults aged 25-50 who have thin gums. The patch is placed during implant surgery to see if it helps the gums heal better and stay healthy. Researchers will check f…
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 03, 2026 12:04 UTC
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New fluoride resin may stop tooth stains from clear aligners
Prevention OngoingThis study tests whether using a fluoride-releasing composite resin for aligner attachments can prevent white spot lesions (early cavities) during clear aligner therapy. Twenty-four people aged 16-24 with mild crowding will have one side of their mouth get the fluoride resin and …
Phase: NA • Sponsor: Mansoura University • Aim: Prevention
Last updated Jun 15, 2026 18:57 UTC
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Fluoride shield: simple varnish may prevent aligner tooth damage
Prevention OngoingThis study tests whether applying fluoride varnish to teeth can prevent white spot lesions (early cavities) that sometimes appear during clear aligner therapy. Twenty-five people aged 16-24 with mild crowding will have one side of their mouth treated with fluoride varnish and the…
Phase: NA • Sponsor: Mansoura University • Aim: Prevention
Last updated Jun 15, 2026 18:55 UTC
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Learning to care: new program boosts confidence for urostomy patients
Symptom relief OngoingThis study tests whether a special education program about stoma care can help urostomy patients improve their self-care skills and life satisfaction. About 60 patients who can communicate and agree to join will take part. The program aims to increase knowledge, confidence, and q…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 16, 2026 12:50 UTC
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Less cutting, less pain: new dental surgery approach shows promise
Symptom relief OngoingThis study compares two ways of doing dental root surgery. One method removes the entire infected area and uses stitches, while the other removes only part of it and uses a medical glue to close the wound. The goal is to see if the gentler method leads to less pain, swelling, and…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 15, 2026 19:08 UTC
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Mirror trick may ease stroke arm pain
Symptom relief OngoingThis study tests whether mirror therapy can improve arm movement and reduce pain in people who have had a stroke. 72 participants with a first-time stroke and arm weakness will be involved. The approach uses a mirror to create the illusion of movement in the affected arm, aiming …
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 15, 2026 19:06 UTC
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Which dental implant makes patients happier? new study compares two designs
Symptom relief OngoingThis study looks at two different ways to replace missing upper teeth in people with severe jawbone loss. Twenty adults will get either a milled bar or a screw-retained dental implant. Researchers will track how satisfied patients are and how often problems like breakage or disco…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 15, 2026 19:05 UTC
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New combo could keep knee surgery patients Pain-Free longer
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether adding dexmedetomidine to standard pain medicine given through an IV during knee surgery can help pain relief last longer. About 100 adults having knee surgery under spinal anesthesia will take part. The goal is to see if this approach reduces the need fo…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 12, 2026 12:07 UTC
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New combo treatment aims to silence jaw pain
Symptom relief OngoingThis study tests whether a mouth splint combined with a granisetron injection into the jaw muscle reduces pain from temporomandibular disorders (TMD) better than a splint alone or with lidocaine. About 48 adults with jaw muscle pain will wear a splint and receive one injection. T…
Phase: PHASE4 • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 10, 2026 13:27 UTC
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New study aims to take the sting out of insulin shots for kids
Symptom relief OngoingThis study compares two simple techniques—applying manual pressure or using a ShotBlocker device—to reduce pain from insulin injections in children aged 6 to 12 with type 1 diabetes. About 108 children will rate their pain during and right after the injection. The goal is to find…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 05, 2026 12:05 UTC
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No-Needle calm: videos and acupressure beat fear of tooth pull for kids
Symptom relief ENROLLING_BY_INVITATIONThis study tests two simple methods—watching a video (audiovisual distraction) and gentle pressure on specific points (acuapoint stimulation)—to see if they help children aged 5-8 feel less anxious and experience less pain during a tooth extraction. 69 healthy kids who need a bab…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 02, 2026 11:57 UTC
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Braces vs. aligners: which moves teeth better?
Knowledge-focused OngoingThis study looks at how clear aligners and traditional braces move teeth in 20 adults with mild crowding. Researchers will measure inflammation markers in gum fluid and track tooth movement using 3D scans to understand the differences. The goal is to help dentists choose the best…
Phase: NA • Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Jun 16, 2026 22:04 UTC
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Scientists compare how different clear aligners hold up after two weeks in the mouth
Knowledge-focused OngoingThis study looks at how two types of clear aligners (single-layer and multi-layer) change after being molded and worn for two weeks. Researchers will measure surface roughness, hardness, and thickness at three points: before molding, after molding, and after wear. Twenty people w…
Phase: NA • Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:54 UTC
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Denture attachment method may affect jawbone loss, study finds
Knowledge-focused OngoingThis study compares two methods of picking up attachments for implant-supported dentures: one done digitally before recording jaw relationships, and the other done directly in the mouth. Ten adults with healthy gums and enough jawbone will be followed for 12 months to measure bon…
Phase: NA • Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:50 UTC
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Vitamin d may keep your dental implants stronger
Knowledge-focused OngoingThis study looks at whether vitamin D levels in the blood affect bone loss around dental implants that support lower dentures. Researchers will measure bone changes and gum health in 40 adults aged 40-60 who already have these implants. The goal is to understand if vitamin D help…
Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC
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3D-Printed tooth fillings face off against traditional materials in 2-Year trial
Knowledge-focused OngoingThis study compares three types of dental onlays (custom-made tooth coverings) for cavities: 3D-printed resin, milled resin, and hybrid ceramic. Researchers will check how well they hold up over 2 years, how strong the bond is to the tooth, and how well they fit. The goal is to s…
Phase: NA • Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:07 UTC
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Dental implant study seeks the most precise placement method
Knowledge-focused OngoingThis study compares two ways of placing four dental implants in people with no teeth. One method uses a full surgical guide, the other a partial guide. Researchers will use scans and X-rays to measure how accurate the implant positions are and how well the replacement teeth fit, …
Phase: NA • Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:08 UTC