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Vitamin d may keep your dental implants stronger

NCT ID NCT07200011

Knowledge-focused Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether vitamin D levels in the blood affect bone loss around dental implants that support lower dentures. Researchers will measure bone changes and gum health in 40 adults aged 40-60 who already have these implants. The goal is to understand if vitamin D helps keep implants healthy, which could improve dental care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Sep 2025

Expected to finish

Oct 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This retrospective study includes adult patients aged 40 to 60 years who have been rehabilitated with unsplinted three-implant mandibular overdentures retained by locator attachments. Only patients with complete clinical records, including serum vitamin D levels and adequate baseline and follow-up periapical radiographs are included. Patients with systemic diseases affecting bone metabolism, history of smoking or alcohol abuse, or medications known to influence bone healing are excluded. The study population are stratified based on serum vitamin D levels into two groups: deficient (\<20 ng/mL) and sufficient (≥30 ng/mL)

Ages

40 to 60 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 40 and 60 years. * Patients rehabilitated with unsplinted three-implant mandibular overdentures retained by LOCATOR attachments . * Availability of recent serum vitamin D records at determined time intervals. * Good general health without uncontrolled systemic diseases. Exclusion Criteria: * Missing or incomplete patient records. * Patients on medications known to affect bone metabolism. * History of smoking or alcohol abuse. * Patients with borderline serum vitamin D values (21-29 ng/mL) to avoid classification bias. * Presence of active oral infections or untreated periodontal disease. * Previous implant failure in the mandible.

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Conditions

The condition(s) this trial relates to.

vitamin D deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Clinical and radiographic effect Implant assesment Radiography Vitamin D deficiency

Contacts and locations

Locations

  • Faculty of Dentistry, Mansoura University

    Al Mansurah, Dakahlia Governorate, 35516, Egypt

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