Cmc Ambroise Paré
Clinical trials sponsored by Cmc Ambroise Paré, explained in plain language.
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Back surgery combo shows promise for spine slip
Disease control CompletedThis study looked at 87 adults with a spine condition called isthmic spondylolisthesis, where one vertebra slips forward. They all had a two-part surgery to fuse the bones together. The results showed the surgery is safe and helps restore normal spine shape and nerve space.
Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Heart surgery lung risk: which ventilation method wins?
Disease control CompletedThis study tested two ways of using a breathing machine during heart bypass surgery to see which one leads to fewer lung problems. Over 1,500 adults having planned heart surgery took part. One group had the breathing machine turned off during bypass, while the other received very…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated May 11, 2026 20:51 UTC
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AI reads heart signals to simplify cancer drug monitoring
Diagnosis CompletedThis study tested whether an artificial intelligence (AI) model can accurately measure heart rhythm changes (QTc) from electrocardiograms (ECGs) in 70 breast cancer patients starting the drug ribociclib. The goal was to see if AI could match or beat standard methods, possibly all…
Sponsor: CMC Ambroise Paré • Aim: Diagnosis
Last updated May 17, 2026 05:37 UTC
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New drug may stop common heart rhythm problem after surgery
Prevention CompletedThis study tested whether a low-dose drug called landiolol can prevent atrial fibrillation (a type of irregular heartbeat) in 400 non-Asian adults after heart surgery. Atrial fibrillation is common after such operations and can lead to complications. The drug was given as a conti…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Prevention
Last updated May 17, 2026 05:31 UTC
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Nerve block may reduce anesthetic needs during heart surgery
Symptom relief CompletedThis study tested whether a parasternal nerve block, given before open-heart surgery, could help control heart rate and blood pressure during the procedure, reducing the need for high doses of anesthetic drugs. The trial involved 35 adults undergoing coronary artery bypass grafti…
Phase: PHASE4 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 17, 2026 05:35 UTC
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Video glasses may reduce sedation during IVF egg retrieval
Symptom relief CompletedThis study tested whether using HappyMed Video Glasses to watch movies during egg retrieval for IVF could reduce the amount of sedative medication needed. 36 women participated, with some using the glasses and others receiving standard care. The goal was to see if distraction cou…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 17, 2026 05:34 UTC
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Knee surgery pain relief gets a boost from sedative drug
Symptom relief CompletedThis study tested whether giving a drug called dexmedetomidine before knee replacement surgery could make pain relief from nerve blocks last longer. 94 adults having planned knee replacement took part. The goal was to see if the drug could delay the need for strong painkillers af…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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No tourniquet, less pain: new combo approach for carpal tunnel surgery
Symptom relief CompletedThis study tested a technique called WALANT (wide awake local anesthesia without a tourniquet) combined with nerve blocks for carpal tunnel release surgery. The goal was to see if this approach reduces pain and improves comfort compared to the standard method that uses a tourniqu…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 11, 2026 20:52 UTC
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Virtual reality beats gas for Post-Surgery pain?
Symptom relief CompletedThis study tested whether using virtual reality (VR) can reduce anxiety and pain in patients recovering from heart surgery, specifically during the removal of chest drainage tubes. 200 adults who had just had heart surgery were randomly assigned to use VR or breathe nitrous oxide…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 07, 2026 18:42 UTC
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No opioids needed? new anesthesia method could ease hip surgery recovery
Symptom relief CompletedThis study looked at whether avoiding opioid painkillers during hip replacement surgery can improve pain control afterward. 80 adults having hip replacement were randomly assigned to receive either standard anesthesia or an opioid-free version using a drug called dexmedetomidine.…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 06, 2026 16:14 UTC
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Local numbing may match standard arm block for carpal tunnel surgery
Symptom relief CompletedThis study tested if a simpler numbing method called WALANT (injecting numbing medicine directly into the wrist) works as well as a standard arm block for carpal tunnel release surgery. 130 adults having endoscopic carpal tunnel release took part. The main goal was to see if WALA…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 01, 2026 16:00 UTC
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Thymus gland may hold key to COVID-19 severity
Knowledge-focused CompletedThis study looked at how the thymus gland, which produces immune cells called T cells, affects COVID-19 severity. Researchers examined 85 hospitalized patients to see if genetic differences in thymus function are linked to worse lung damage. The goal was to better understand why …
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Liver ultrasound may predict heart failure after surgery
Knowledge-focused CompletedThis study looked at 32 adults who had heart surgery to see if a liver ultrasound could help find right-sided heart problems. Right heart issues are common after surgery and can lead to kidney or liver failure. The researchers measured blood flow in the liver and compared it to s…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Routine ICD testing under review: does it help or harm?
Knowledge-focused CompletedThis study followed 143 people with implantable defibrillators (ICDs) who needed a replacement. Researchers checked whether routine defibrillator testing during the replacement procedure is safe and helps find device problems. The goal was to better understand how to manage these…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Smart wristband tracks heart surgery recovery steps
Knowledge-focused CompletedThis study tested whether a simple electronic wristband could help track how much patients move after heart surgery. 137 adults wore the band for two months after leaving the hospital. The goal was to measure daily steps and find early signs of recovery or complications.
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC
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Can a stiff limb deepen your hypnosis? new study investigates
Knowledge-focused CompletedThis study looked at whether making a person's arm or leg stiff (catalepsy) helps them go into a deeper hypnotic trance. Researchers measured changes in the body's 'rest and digest' nervous system using a special monitor. 90 healthy volunteers took part to see if this common hypn…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 11, 2026 20:49 UTC
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Can a simple ultrasound predict bladder leak severity?
Knowledge-focused CompletedThis study looked at whether ultrasound measurements of the urethra can help predict how severe urinary incontinence is in women. Researchers measured the length and angle of the urethra in 50 adult women. The goal was to see if these measurements could be used to forecast incont…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 11, 2026 20:47 UTC
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Hands-Free anesthesia: no mask needed?
Knowledge-focused CompletedThis study tested whether a device that delivers warm, moist oxygen through the nose (Optiflow) could replace the traditional face mask during the start of anesthesia. Sixty adults having surgery with general anesthesia took part. The goal was to see if this method could make the…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 11, 2026 20:39 UTC
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Scientists map a hidden tendon that could explain arm injuries
Knowledge-focused CompletedThis study looked at a recently discovered tendon called the delto-pectoral tendon (DPT) in the chest muscle. Researchers used ultrasound to see and measure this tendon in 46 adults with upper limb problems. The goal was to understand its role and how it relates to other tendons,…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 04, 2026 16:31 UTC
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Researchers track hidden breathing risk after heart operations
Knowledge-focused CompletedThis study aimed to find out how often patients develop lasting diaphragm weakness after heart surgery. Researchers followed 157 patients who had open-heart surgery, using ultrasound scans to check diaphragm movement. The goal was to understand how often this weakness happens and…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Apr 22, 2026 15:58 UTC