Cmc Ambroise Paré
Clinical trials sponsored by Cmc Ambroise Paré, explained in plain language.
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Simple stretch may speed diaphragm recovery after heart surgery
Disease control CompletedThis study investigates whether adding a contract-relax physical therapy technique to standard respiratory care can improve diaphragm function in patients who develop diaphragmatic paresis after cardiac surgery. The trial enrolls adults who have undergone heart surgery with a hea…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Could cheap steroids help hearts in shock?
Disease control CompletedThis study tested whether giving low doses of two steroids (hydrocortisone and fludrocortisone) helps adults with cardiogenic shock, a life-threatening condition where the heart can't pump enough blood. 380 participants received either the steroids or a placebo. The main goal was…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Heart surgery breathing study aims to cut lung failure risk
Disease control CompletedThis study tested two ways of managing breathing during heart bypass surgery to see which better prevents lung complications. Over 1,500 adults having planned heart surgery were randomly assigned to either no breathing support or gentle, low-volume breaths while on the heart-lung…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Double fusion surgery shows promise for slipped vertebrae
Disease control CompletedThis study looked at 87 adults who had a two-step spinal fusion surgery for isthmic spondylolisthesis, a condition where a vertebra slips forward. The surgery combines an anterior approach (through the abdomen) with a posterior approach (through the back) to stabilize the spine. …
Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Heart drug shows promise in preventing post-surgery rhythm disorder
Prevention CompletedThis study tested whether a low-dose infusion of landiolol, a short-acting beta-blocker, could prevent atrial fibrillation in 400 non-Asian patients after cardiac surgery. Participants received either landiolol or a placebo for up to 48 hours after surgery. The goal was to see if…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Prevention
Last updated Jun 27, 2026 12:05 UTC
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New foot block may get you walking faster after surgery
Symptom relief CompletedThis study tested a new way to numb only the front part of the foot for surgery, leaving the heel sensation intact. The goal was to see if this approach could provide good pain relief while allowing patients to walk earlier. Twenty-seven adults having foot surgery received a targ…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Heart surgery bowel breakthrough? drug may speed recovery
Symptom relief CompletedThis study tested whether naloxegol, a drug used for constipation caused by painkillers, can help people who had heart surgery recover normal bowel function faster. About 305 adults participated. The goal was to see if taking naloxegol around the time of surgery reduces the time …
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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New numbing technique could make hand surgery simpler and faster
Symptom relief CompletedThis study tested if a simpler numbing method called WALANT works as well as a standard arm block for carpal tunnel release surgery. WALANT involves injecting numbing medicine directly into the wrist area, avoiding the need for a tourniquet or sedation. The trial included 130 adu…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Opioid-Free anesthesia shows promise for hip surgery pain
Symptom relief CompletedThis study tested whether using a drug called dexmedetomidine instead of opioids during hip replacement surgery could reduce pain and the need for strong painkillers afterward. 80 adults undergoing hip replacement took part. The goal was to see if this approach leads to better pa…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Could a sedative drug extend pain relief after knee surgery?
Symptom relief CompletedThis study tested whether giving the sedative drug dexmedetomidine during knee replacement surgery could lengthen the time before patients need additional painkillers. 94 adults having elective knee replacement under regional anesthesia received either the drug or a placebo. The …
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Video glasses may help women need less sedation during IVF egg retrieval
Symptom relief CompletedThis study tested whether wearing HappyMed video glasses (which play films or concerts) during egg retrieval for IVF could reduce the amount of sedative drugs needed. 36 women were randomly assigned to use the glasses or receive standard care. The goal was to see if distraction c…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Chest injection may lower anesthetic doses during heart surgery
Symptom relief CompletedThis study tested whether a parasternal block—an injection of the numbing drug ropivacaine into the chest wall—could reduce the amount of anesthetic needed to keep heart rate and blood pressure stable during coronary artery bypass surgery. Thirty-five patients were randomly assig…
Phase: PHASE4 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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No tourniquet, less pain: new combo approach for hand surgery
Symptom relief CompletedThis study tested whether using the WALANT technique (numbing the hand with local anesthetic and epinephrine) along with nerve blocks at the wrist could make carpal tunnel release surgery more comfortable than using a standard tourniquet. 60 adults having endoscopic carpal tunnel…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Virtual reality beats gas for Post-Surgery pain?
Symptom relief CompletedThis study tested whether using virtual reality (VR) can help reduce pain and anxiety in people recovering from heart surgery, specifically when chest tubes are removed. 200 adults who had just had heart surgery were given either VR or nitrous oxide (laughing gas) during the proc…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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No mask needed? new device may simplify anesthesia start
Symptom relief CompletedThis study tested whether a device called Optiflow, which delivers warm, humidified oxygen through the nose, could replace the usual face mask during the start of anesthesia. The goal was to see if it could safely oxygenate patients without needing to hold a mask on their face. S…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Study checks if testing heart devices during replacement is worthwhile
Knowledge-focused CompletedThis study followed 143 people who had a defibrillator (ICD) replaced to see if testing the device's ability to deliver a shock is safe and useful. The test involves briefly inducing a fast heart rhythm under anesthesia. The goal was to check for device problems, like abnormal sh…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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AI reads heart signals to simplify cancer drug monitoring
Knowledge-focused CompletedThis study tested whether an artificial intelligence (AI) model can accurately measure heart rhythm changes (QTc) from ECGs in 70 breast cancer patients starting the drug ribociclib. The goal was to see if simpler ECG devices could work as well as standard 12-lead machines when a…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Smart wristband tracks heart surgery recovery
Knowledge-focused CompletedThis study tested whether a simple electronic wristband could help doctors understand how patients recover after heart surgery. 137 adults wore the wristband for two months after leaving the hospital, and it counted their daily steps. The goal was to measure when patients returne…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Scientists map a new tendon in the shoulder using ultrasound
Knowledge-focused CompletedThis completed study used ultrasound to look at a recently discovered tendon in the shoulder called the delto-pectoral tendon (DPT). Researchers examined 46 adults with upper limb injuries to measure this tendon and understand how it connects with other shoulder structures. The g…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Heart surgery patients: one in six may face hidden diaphragm trouble
Knowledge-focused CompletedThis study tracked 157 heart surgery patients to see how many still have a weak diaphragm 7 days after their operation. Using ultrasound, researchers measured diaphragm movement during breathing and sniffing. The goal is to understand how common persistent diaphragm problems are …
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Hypnosis breakthrough? scientists test if body stiffness deepens trance
Knowledge-focused CompletedThis study looked at whether catalepsy (a state of rigid body posture) helps people go into a deeper hypnotic trance. Researchers measured relaxation through a heart monitor in 90 healthy volunteers. The goal was to see if adding body dissociation makes hypnosis more intense.
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Could your thymus gland determine COVID-19 severity?
Knowledge-focused CompletedThis study looked at how the thymus gland, which produces immune cells called T cells, might influence COVID-19 severity. Researchers compared 85 hospitalized patients with and without COVID-19 to see if genetic differences in thymus function were linked to worse lung damage. The…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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New ultrasound method may predict how bad urinary leakage gets
Knowledge-focused CompletedThis study looked at whether special ultrasound measurements of the urethra can predict how severe a woman's stress urinary incontinence (leaking urine when coughing, sneezing, or exercising) will be. Researchers measured the length and angle of the urethra in 50 adult women. The…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Liver ultrasound may spot hidden heart trouble after surgery
Knowledge-focused CompletedThis completed study tested whether a liver ultrasound could detect right-sided heart failure after cardiac surgery. Researchers measured blood flow in the portal vein using Doppler ultrasound in 32 high-risk patients within 24 hours of surgery. The goal was to see if this simple…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC