Heart surgery patients may get relief from Post-Op constipation with naloxegol

NCT ID NCT04433390

First seen May 21, 2026 · Last updated May 23, 2026 · Updated 1 time

Summary

This study tested whether naloxegol, a drug used for opioid-induced constipation, can shorten the time it takes for bowel function to return after heart surgery. 305 adults undergoing cardiac surgery with a heart-lung machine were randomly assigned to receive naloxegol or a placebo. The goal was to see if the drug could reduce postoperative ileus (temporary bowel paralysis) and related complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for POSTOPERATIVE ILEUS (POST CARDIAC SURGERY CONSTIPATION) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • CMC Ambroise Paré

    Neuilly-sur-Seine, Neuilly Sur Seine, 92200, France

Conditions

Explore the condition pages connected to this study.