City Of Hope Medical Center

This early-stage trial tested the safety and best dose of an investigational drug called flotetuzumab. It involved 13 adults with advanced blood cancers that had returned or stopped responding to standard treatments. The main goal was to understand the drug's side effects and see…

This study tested whether giving very high doses of chemotherapy, followed by a patient's own stem cells to 'rescue' their immune system, could better treat a rare and aggressive form of breast cancer called inflammatory breast carcinoma. It involved 41 patients with stage IIIB d…

This study tested a treatment to help prevent acute myeloid leukemia (AML) from returning after initial remission. For patients aged 60 or younger, doctors used high-dose chemotherapy and radiation to wipe out the bone marrow, then gave back the patient's own previously collected…

This study tested a new, targeted form of radiation therapy combined with chemotherapy and a donor stem cell transplant for adults with acute leukemia that had not responded well to standard treatments. The main goals were to find the safest dose of the new radiation and to see i…

This small pilot study tested whether an 8-week home exercise program delivered via video calls is practical and helpful for lymphoma survivors. The goal was to see if regular, guided workouts could improve heart health and reduce future cardiovascular risks in people who had fin…

This early-stage trial tested a new three-drug combination for people with advanced colorectal cancer that had spread and stopped responding to standard chemotherapy. The main goal was to find the safest dose of the drug regorafenib when given with two immunotherapy drugs (nivolu…

This study tested a new type of blood test that uses artificial intelligence to look for tiny signs of hidden cancer spread in patients with a type of bile duct cancer. The goal was to see if this test could accurately identify patients whose cancer had already spread in ways tha…

This study tested a new blood test designed to find hidden liver cancer spread in people with pancreatic cancer before they have surgery. The test looks for tiny particles released by the cancer into the blood. The goal is to help doctors better identify which patients are at hig…

This study tested a new blood test designed to help doctors decide which colon cancer patients need chemotherapy after surgery. The test looks for tiny signs of leftover cancer cells to identify patients at high risk of the cancer coming back. The goal is to give chemotherapy onl…

This study tested a new blood test to see if it could accurately detect whether a type of liver cancer called intrahepatic cholangiocarcinoma (bile duct cancer) had spread to nearby lymph nodes before a patient's surgery. The goal was to help doctors decide the best surgical plan…

This study tested a new blood test to detect a rare but aggressive liver cancer called intrahepatic cholangiocarcinoma. Researchers analyzed tiny genetic signals in the blood of 535 people to see if they could accurately identify the cancer. The goal is to create a simpler, non-i…

This study tested whether using at-home devices like scales, blood pressure cuffs, and activity trackers could help monitor patients recovering from major cancer surgery. It involved 22 patients with various cancers of the digestive, urinary, or reproductive systems. The goal was…