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Islet transplants after kidney transplants: a step toward insulin freedom?

NCT ID NCT00708604

Completed Disease control Sponsor: City of Hope Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tested whether transplanting insulin-making islet cells could help people with type 1 diabetes who already had a kidney transplant. Only 3 patients took part, and they stayed on anti-rejection drugs. The goal was to see if the procedure was safe and could reduce or stop the need for insulin shots.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Islet cell transplant
What this could lead to
If successful, this approach could help some people with type 1 diabetes reduce or stop insulin injections after a kidney transplant.
What could go wrong
This was a very small, early-phase trial with only 3 participants, so results may not apply widely. Lifelong anti-rejection drugs are still needed, and the transplant itself carries risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS

Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

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