TYPE 2 DIABETES MELLITUS (T2DM)

This study tests whether the drug finerenone can reduce protein in the urine (a sign of kidney damage) in adults with type 2 diabetes and chronic kidney disease. About 148 participants will receive either finerenone or a placebo pill daily for 6 months, on top of their usual medi…

This study tests a new, simpler weight training program called D-STORM for adults with type 2 diabetes. The program uses easier exercises to build muscle and improve blood sugar control. Over 12 weeks, 56 participants will either do the training plus usual care or just usual care…

This study tests a new medicine called bofanglutide (GZR18) for adults with type 2 diabetes whose blood sugar is not well controlled with metformin alone. Bofanglutide is given as a shot under the skin every two weeks, and researchers compare it to semaglutide, a weekly injection…

This early-stage trial tests a single injection of UBT38006 in 43 healthy adult men to see if it is safe and how the body processes it. Participants receive either the drug, a placebo, or an active comparator (insulin degludec). The goal is to gather safety data and measure drug …

This study tests a new tool called the Snouda Metabolic Score (SMS) that helps doctors identify the specific metabolic problems driving Type 2 Diabetes in each patient. 150 adults will follow a personalized 24-week lifestyle and nutrition plan based on their SMS results. The goal…

This study compares two glucose monitoring methods—continuous glucose monitors (CGM) and traditional finger-prick tests—in adults with type 2 diabetes who are taking the drug dapagliflozin. The 120 participants will be split into two groups and followed for 12 weeks to see which …

This study tests a 12-week digital program led by a nurse to help young adults (ages 18-45) with type 2 diabetes better manage their condition. Participants use a web or mobile app for education, goal-setting, and direct messaging with a nurse. The goal is to see if this approach…

This study tests whether taking a daily supplement made from bitter melon extract and snakehead fish powder can help lower blood sugar in adults with type 2 diabetes. About 80 participants will take either the supplement or a placebo for 4 weeks. The goal is to see if this natura…

This Phase 3 trial will test whether glimepiride, a standard diabetes pill, can reduce the risk of heart-related death, heart transplant, or worsening heart failure in people with type 2 diabetes and chronic heart failure. About 1,484 participants will receive either glimepiride …

This study tests whether a personalized diet, exercise, sleep, and counseling program can help adults with type 2 diabetes achieve remission. 120 participants will follow the program for 6 months, then be monitored for another 12. The goal is to see if blood sugar levels can retu…

This study tests whether adding WhatsApp-based education and counseling to standard care helps stroke patients with type 2 diabetes improve their lifestyle, blood sugar control, and disease knowledge. 84 participants will be split into two groups: one gets routine education, the …

This study tests whether individualized nursing interventions and education can help people with type 2 diabetes better manage their blood sugar levels. Researchers will provide personalized care and follow-up to 72 participants, measuring blood glucose, HbA1c, and self-managemen…

This study tests a 6-month treatment regimen containing pretomanid for people with drug-resistant tuberculosis who also have type 2 diabetes. Researchers will compare how well the treatment works and how safe it is in diabetic patients versus non-diabetic patients. The goal is to…

This Phase 2 study tests an experimental drug called PG-102, given as a weekly injection, in 80 adults with type 2 diabetes. Participants will receive either PG-102, a placebo, or the approved drug semaglutide for 24 weeks. The main goal is to see how well PG-102 lowers blood sug…

This study tests whether a 12-week virtual health coaching program powered by artificial intelligence can improve blood sugar control in adults with type 2 diabetes. 206 participants in Indonesia will be randomly assigned to use the DIACOACH app or receive standard diabetes educa…

This study will test whether a diet with carefully chosen carbohydrates can improve blood sugar control in people with type 2 diabetes. 150 adults will try both an optimized carbohydrate diet and a standard diabetes diet for 12 weeks each, with a break in between. The goal is to …

This study tests a three-session training program to help older adults (65+) who use insulin learn to use a continuous glucose monitor (CGM). Participants will be randomly assigned to the program or standard training. The goal is to see if the program improves how often they wear…

This study will test a mindfulness-based education program for adults with type 2 diabetes. The goal is to see if it reduces diabetes-related distress and helps people feel more empowered to manage their condition. 70 participants will take part in group sessions that combine min…

This study tests whether a structured storytelling education program can help adults with type 2 diabetes improve their blood sugar control. About 226 participants will either receive standard care or standard care plus two face-to-face storytelling sessions and four brief phone …

This study tests whether aromatherapy foot massage can reduce neuropathic pain in people with type 2 diabetes. 78 participants will massage their feet for 10 minutes, three times a week for 4 weeks. Researchers will compare the effects of an aromatherapy oil versus a plain oil to…

The EXPAND study is a research project that will enroll 440 adults with and without pancreatic conditions to understand why type 2 diabetes varies so much from person to person. Researchers will collect data on metabolism, genetics, and pancreas health to identify distinct diabet…

This study will test two new non-invasive devices (HEMI and SPG-NINOX) that measure small blood vessel function in 165 adults. Participants include healthy volunteers and people with high blood pressure, type 2 diabetes, or chronic kidney disease. The goal is to see if these devi…

This study follows 2,500 adults in Mexico aged 18 to 65 who do not yet have type 2 diabetes or high blood pressure. Over five years, researchers will track their health through yearly check-ups, blood tests, and lifestyle questionnaires. The goal is to identify what factors incre…

This observational study in Mexico will follow 30 adults already taking tirzepatide for conditions like diabetes or obesity. Researchers will use MRI scans of the knees, CT scans of the heart, and body composition tests to see how the drug affects cartilage, heart fat, and overal…

This pilot study tests whether fecal microbiota transplantation (FMT) can change the gut microbiome in 30 people with type 2 diabetes and stable coronary artery disease. Participants receive processed stool from healthy donors via colonoscopy. The goal is to see if this alters gu…

This study looks at how two common artificial sweeteners, sucralose and saccharin, affect blood sugar control and gut bacteria in adults with type 2 diabetes. Over 33 participants will take each sweetener or a placebo for one week, with breaks in between. The goal is to see if th…