New diabetes shot aims to beat semaglutide in early trial

NCT ID NCT07187856

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This Phase 2 study tests an experimental drug called PG-102, given as a weekly injection, in 80 adults with type 2 diabetes. Participants will receive either PG-102, a placebo, or the approved drug semaglutide for 24 weeks. The main goal is to see how well PG-102 lowers blood sugar (HbA1c) compared to placebo, with additional checks on weight changes and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
PG-102 (an experimental drug injected weekly)
What this could lead to
If successful, PG-102 could offer a new weekly injection option to help control blood sugar and possibly reduce weight in people with type 2 diabetes.
What could go wrong
This is an early Phase 2 trial with only 80 participants, so results may not apply to everyone. The drug may not work better than existing treatments like semaglutide, and side effects are still being studied.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Emeritus Research

    Camberwell, Victoria, 3124, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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