TYPE 2 DIABETES MELLITUS (T2DM)

This study tests a digital reminder tool (DIPAR) for adults with type 2 diabetes. The tool, accessed through a patient portal, reminds patients and doctors to check kidney function and blood sugar levels regularly. The goal is to see if these reminders help more patients get the …

This study tests a new medicine called GZR18 in about 1,100 Chinese adults with type 2 diabetes whose blood sugar is not well controlled by metformin alone or with other diabetes pills. Participants receive either GZR18 or an active comparator to see which works better at lowerin…

This study looks at how changing when you eat and improving sleep can help people with type 2 diabetes, high blood pressure, or obesity better control their blood sugar, heart health, and weight. About 40 adults will receive personalized nutrition advice and education. The goal i…

This study tests a new medicine called maridebart cafraglutide to see if it helps control blood sugar in adults with type 2 diabetes. About 409 people will receive either the drug or a placebo for 24 weeks. Researchers will measure changes in blood sugar levels and body weight.

This study tests whether regular text messages can help adults in Nepal better manage their type 2 diabetes. 154 participants will either receive standard care alone or standard care plus text messages with tips and reminders. After 6 months, researchers will check blood sugar le…

This early-phase study tests whether rosemary extract can improve markers of oxidative stress and inflammation in 40 adults with type 2 diabetes. Participants take either rosemary extract or a placebo for 12 weeks. The goal is to see if this natural supplement can support diabete…

This study is testing a new magnetic system (MagDI) that creates a connection in the small intestine to help with weight loss and blood sugar control in adults with obesity and type 2 diabetes. The device is placed using a tube through the mouth, avoiding surgery. The study will …

This study aimed to see if a single pill combining two diabetes drugs could control blood sugar better than taking them separately in people with type 2 diabetes already on metformin. It planned to enroll adults with HbA1c between 7.5% and 10%. However, the study was withdrawn be…

This study tests whether exercise, brain training, or both can improve physical and mental abilities in adults 60 and older who have had a stroke and also have high blood pressure or diabetes. About 444 participants from community health centers in five Chinese cities will take p…

This study tests a new weekly injection called CT-388 in 360 adults who are overweight or obese and have type 2 diabetes. The goal is to see if it helps with weight loss and lowers blood sugar over 48 weeks. Participants will receive either the study drug or a placebo, and neithe…

This study tests two new injectable medicines for adults with type 2 diabetes whose blood sugar is not well controlled with current GLP-1 drugs. One shot is given once a week, the other every two weeks. The goal is to see which works better and is safer for lowering blood sugar a…

This study tests an experimental injection called GZR18 in 274 Chinese adults with type 2 diabetes whose blood sugar is not well controlled by diet and exercise alone. The goal is to see if the drug safely lowers blood sugar and helps with weight loss. Participants receive either…

This study tests a 12-week telenursing program where nurses provide diabetes education and support via video calls to adults with type 2 diabetes in Thailand. Participants must have poorly controlled blood sugar and own a smartphone. The goal is to see if this approach is practic…

This study tests a new approach to help 80 adults with type 2 diabetes use data from wearable glucose monitors and activity trackers to improve their daily self-care. Participants will receive personalized coaching based on their device data to help with medication, diet, and exe…

This early-stage study is testing how two experimental diabetes drugs (L03RD1 and L03RD2) work when given together, compared to a third drug (L03TD1) given alone. It involves 48 healthy adults aged 19 to 55. The main goal is to measure drug levels in the blood and check for any s…

This study tracks 50 obese adults (BMI over 32) who are having weight-loss surgery. Researchers use MRI scans and blood tests before and up to 6 months after surgery to measure fat in the pancreas and check how well the pancreas makes insulin. The goal is to see if losing pancrea…

This study looks at whether a common diabetes medicine called SGLT2 inhibitor can help people with type 2 diabetes who have had a heart attack. Researchers will compare health records of 200,000 people in Korea who took either an SGLT2 inhibitor or another diabetes drug after the…

This pilot study tests whether diabetes care can be successfully integrated into two primary healthcare centers in Abuja, Nigeria. Researchers will screen, diagnose, treat, and educate 106 adults with uncomplicated type 2 diabetes. The goal is to see if this approach is feasible …

This study looks at how long you need to fast and what happens when you temporarily stop taking dulaglutide (a diabetes drug) on how much food stays in your stomach after a meal. About 20 people with type 2 diabetes will have their stomachs checked with ultrasound after a test me…