New shot aims to tackle obesity and diabetes together

NCT ID NCT06845202

Recruiting now Disease control Sponsor: Alnylam Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests an experimental drug called ALN-4324 in two groups: healthy overweight volunteers and overweight patients with type 2 diabetes. The goal is to check the drug's safety and how well it controls blood sugar. Participants receive either the drug or a placebo, and researchers monitor side effects and blood sugar levels over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESE OR OVERWEIGHT HEALTHY VOLUNTEERS TYPE 2 DIABETES MELLITUS (T2DM)

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Clinical Trial Site
COMPLETED

Montclair, California, 91763, United States
Clinical Trial Site
COMPLETED

Washington D.C., District of Columbia, 20009, United States
Clinical Trial Site
COMPLETED

Miami, Florida, 33126, United States
Clinical Trial Site
COMPLETED

Marlton, New Jersey, 08053, United States
Clinical Trial Site
COMPLETED

Monroe, North Carolina, 28112, United States
Clinical Trial Site
COMPLETED

Dallas, Texas, 75230, United States
Clinical Trial Site
COMPLETED

Dallas, Texas, 75246, United States
Clinical Trial Site
COMPLETED

Buenos Aires, C1060, Argentina
Clinical Trial Site
COMPLETED

Buenos Aires, C1061AAE, Argentina
Clinical Trial Site
COMPLETED

Buenos Aires, C1061, Argentina
Clinical Trial Site
COMPLETED

San Miguel de Tucumán, T4000IHE, Argentina
Clinical Trial Site
COMPLETED

Concord, L4K 4M2, Canada
Clinical Trial Site
RECRUITING

Mount Royal, H3P 3P1, Canada
Clinical Trial Site
COMPLETED

Vancouver, V5Y 3W2, Canada
Clinical Trial Site
COMPLETED

Santiago, 7500710, Chile
Clinical Trial Site
COMPLETED

Santiago, 7770086, Chile
Clinical Trial Site
COMPLETED

Santiago, 8320000, Chile
Clinical Trial Site
COMPLETED

Essen, 45355, Germany
Clinical Trial Site
COMPLETED

Gdansk, 80-546, Poland
Clinical Trial Site
COMPLETED

Tarnów, 33-100, Poland
Clinical Trial Site
COMPLETED

Warsaw, 02-507, Poland
Clinical Trial Site
COMPLETED

Wroclaw, 51-162, Poland