STROKE, ACUTE

This study tests whether sending stroke patients straight to a special X-ray room (angio suite) for imaging and treatment can speed up care and improve recovery. About 594 adults with severe stroke symptoms will be randomly assigned to either the new fast-track approach or the us…

This study tests whether a newer clot-busting drug (tenecteplase) works better than the standard drug (alteplase) when given before a mechanical procedure to remove a large blood clot from the brain. About 850 adults who have had a severe stroke within the last 4.5 hours will be …

This study tests whether adding a gentle brain stimulation technique (rTMS) to standard swallowing therapy can lower the chance of pneumonia in people who have trouble swallowing after a stroke. About 70 adults with moderate to severe swallowing difficulty will be enrolled. The g…

This study is testing different doses of the clot-busting drug tenecteplase in 4,000 people who have had a stroke caused by a blood clot. The goal is to find the safest and most effective dose, especially for patients who are also on blood thinners or undergoing a procedure to re…

This study tests a telehealth weight-loss program designed for people who have had a stroke. The goal is to help participants lose weight and improve their health, especially those who have limited access to in-person programs. About 94 adults who are at least one year past their…

This study tests whether removing blood clots from the brain up to 72 hours after a stroke can help patients recover better, even when only a basic CT scan is available. Currently, this treatment is only proven within 6 hours and requires advanced imaging that many hospitals lack…

This study looks at whether a procedure called endovascular thrombectomy (EVT) helps people who already have a moderate-to-severe disability and then have a major stroke. About 1,060 adults will be randomly assigned to get EVT or standard medical care. The goal is to see if EVT i…

This study looks at two approaches for treating adults who have a severe stroke caused by a blocked large artery in the brain. One approach sends patients directly to a special procedure room (angiography suite) for clot removal, while the other starts with evaluation in the emer…

This study tests a wearable device that helps stroke survivors improve arm movement by retraining how muscles work together. The device gives feedback on individual muscle activity to reduce abnormal co-contraction. The study will enroll 96 people who have had a stroke, either re…

This study tests a new approach called 'One-Stop management' for treating severe strokes. Instead of moving patients between a CT scan room and a treatment room, both the brain scan and the clot-removal procedure happen in one room. The goal is to save time and improve recovery. …

This study tests whether a non-invasive nerve stimulation (tVNS) applied to the ear or neck, combined with task-specific training, can improve arm movement, thinking skills, and quality of life in people who had a stroke 3–6 months ago. 54 participants will be randomly assigned t…

This study tests whether a low-cost virtual reality (VR) platform can help people recover arm movement after a first-time stroke. Forty adults with moderate to severe arm weakness will either receive VR therapy plus standard care or standard care alone. Researchers will measure m…

This study looks at whether a nurse-led transitional care program helps stroke survivors in Tanzania feel more prepared to leave the hospital, manage their health, and have a better quality of life. About 130 stroke survivors, their caregivers, and healthcare workers will be foll…

This study is testing a new type of MRI scanner, called Field-Cycling Imaging (FCI), to see if it can detect changes in the brain within the first 24 hours of a stroke. The goal is to find out if FCI can identify brain tissue that might recover. About 40 adults who have had a str…

This study is tracking 350 adults with severe stroke caused by a blocked large artery in the brain. Researchers want to see how well a procedure called endovascular thrombectomy (which removes the clot) works in real-world hospitals across Asia-Pacific, not just in controlled cli…

This study examines tiny RNA molecules in the blood of 300 adults who had a stroke and received a procedure to remove the clot. Researchers want to see if certain RNA patterns can help predict how well patients recover. The goal is to find new markers that could guide future stro…

This study is testing whether brain scans and a technique called transcranial magnetic stimulation can predict how well someone will recover arm movement after a stroke. Researchers will collect data from 657 adults who recently had a stroke and have arm weakness. The goal is to …

This study aims to understand if COVID-19 vaccines have any impact on brain health. Researchers will use MRI scans to look at the brains of 500 healthy adults in Hong Kong, comparing scans taken before and after vaccination. The goal is to provide clear, evidence-based informatio…

This study aims to improve how emergency call operators identify life-threatening conditions like heart attack, stroke, and breathing problems over the phone. Researchers will analyze millions of past emergency calls using artificial intelligence to find patterns that help spot s…

This study looks at the clots removed from people having a stroke to understand how their composition relates to blood markers, how well treatment works, and the cause of the stroke. Researchers will analyze 1,200 patients' clots and blood samples. The goal is to learn more about…

This study looks at whether a simple CT scan can be used instead of more advanced scans to decide if stroke patients should have a procedure to remove a blood clot. About 1,846 adults who had a stroke within the last 24 hours will take part. The goal is to see if the simple scan …

This observational study aims to see if a new, standardized physical exam can reliably find joint motion problems in healthy adults and in people hospitalized after a stroke or mini-stroke (TIA). Researchers will compare exam results between groups and check if motion issues rela…

This study looks at whether fusing 3D scans with live X-ray images helps doctors reach and remove blood clots in the brain more quickly during a standard stroke procedure. About 300 adults having clot removal will be included. The goal is to see if this imaging technique improves…

This study is following 5,000 adults in Hong Kong who either have a brain disease (like stroke or dementia) or are at high risk. Researchers will collect medical records and survey data over time to identify what factors lead to brain diseases. The goal is to find ways to keep br…

This study collects data on how well patients recover neurologically 3 months after endovascular treatment for an acute ischemic stroke. It involves 5,000 participants and focuses on a key recovery score that is rarely measured at this stage. The goal is to better understand pati…

This study aims to understand how a protein called BD-tau, which is released into the blood when the brain is injured, changes over time in people having a stroke. Researchers will take blood samples every hour for 48 hours from 100 adults with acute ischemic stroke. The goal is …