Stroke care showdown: direct to treatment vs. emergency room first

NCT ID NCT06825897

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether taking stroke patients straight to the angiography suite for clot removal, instead of first evaluating them in the emergency department, leads to better recovery. About 2,000 adults with severe stroke symptoms within 7 hours will be randomly assigned to one of the two approaches. The goal is to see if skipping the ER reduces disability and improves outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Direct transfer to angiography suite (procedure)

What this could lead to

If this works, it could show that sending stroke patients straight to the treatment room speeds up care and leads to better recovery with less disability.

What could go wrong

This is a large trial, but it's testing a process change, not a new drug. Results may vary across hospitals, and some patients might need emergency department evaluation that skipping could miss.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Ischemic Stroke large artery stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • HMH Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Henry Ford Health System

    RECRUITING

    Detroit, Michigan, 48202, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Research Foundation for SUNY on behalf of University at Buffalo

    RECRUITING

    New York, New York, 14203, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Iowa

    NOT_YET_RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Email: •••••@•••••

  • University of Michigan Health-West

    RECRUITING

    Wyoming, Michigan, 49519, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••