SHOCK

This study looked at 120 critically ill patients with acute kidney injury and shock who needed dialysis. Researchers compared a special method called sodium profiling dialysis to standard dialysis to see if it helped keep blood pressure stable and reduced fluid buildup in the lun…

This study tested whether methylene blue, a dye that affects blood vessel function, can prevent dangerous drops in blood pressure during kidney dialysis. It involved 261 critically ill adults with acute kidney injury who needed dialysis. The goal was to see if the treatment could…

This study tested whether penehyclidine hydrochloride can improve microcirculation in critically ill children with shock better than the standard drug atropine. 98 children aged 28 days to 18 years who still had poor blood flow despite stable blood pressure took part. The main go…

This large study tested whether a 'balanced' fluid (Lactated Ringer) is better than normal saline for children with septic shock. Over 9,000 kids participated across multiple hospitals. The goal was to see which fluid reduces the risk of serious kidney problems or death within 30…

This study tested whether it is possible to set personalized blood pressure targets for critically ill patients using a brain oxygen monitor. Sixteen ICU patients on breathing machines or shock medications had their blood pressure adjusted to match individual brain blood flow nee…

This study tested whether a special type of dialysis (high-permeability hemodialysis) could help people in shock after being revived from cardiac arrest. The idea was to filter out inflammatory substances from the blood to improve blood pressure and reduce the need for strong med…

This study looked at whether a simple ultrasound of the jugular vein and certain shock indices can predict low blood pressure after spinal anesthesia in C-sections. Researchers measured the jugular vein collapsibility index and several shock indices in 60 pregnant women. The goal…

This study tested whether adding the oral drug midodrine to standard IV norepinephrine helps critically ill patients with shock stop IV blood pressure support sooner. 112 stable ICU patients on low-dose norepinephrine were included. The goal was to see if midodrine shortens weani…

This study compares two methods for measuring stroke volume (how much blood the heart pumps) in people with shock. It will enroll 30 critically ill adults in the ICU. Researchers will use both an ultrasound (echocardiography) and a noninvasive monitor (bioreactance) to see how we…

This study observed over 1,600 adults in French emergency rooms to understand how patients are managed in the resuscitation area and whether being admitted directly to that area versus later affects their need for intensive care within 24 hours. Researchers recorded patient detai…

This study compared a non-invasive device (ClearSight) with a standard invasive method (transpulmonary thermodilution) for measuring heart function in 42 ICU patients with shock or low cardiac output. The goal was to see if the non-invasive device could be used routinely. Researc…

This study looked at 50 shock patients on ventilators to see if their breathing effort changes the accuracy of an ultrasound test that measures a large vein in the belly. Doctors used the test to predict whether giving fluids would help the heart pump more blood. They found that …

This study looked back at medical records of 18 intensive care patients who received hydroxocobalamin (a form of vitamin B12) for severe vasodilatory shock, a condition where blood vessels widen too much and blood pressure drops dangerously. The goal was to see if the treatment c…

This study looked at 800 emergency ICU patients to see if simple checks and gut feelings from nurses and students can predict who will survive, just as well as complex scoring systems. The goal was to collect data and compare different prediction methods to find the easiest and m…

This study tested whether ultrasound measurements of the heart and blood vessels can predict which mechanically ventilated children will benefit from extra fluids. Only about half of children with shock respond to fluids, and too much fluid can be harmful. The researchers used a …

This study looked at whether giving nutrition through a tube into the stomach (enteral) or through a vein (parenteral) early on affects survival in very sick patients who need a breathing machine and heart-support medications. Over 2,400 adults in intensive care units were random…

This study tested a simple bedside test—a 15-second pause in breathing—to see if it could predict whether infants in shock would benefit from more fluids. Ten infants under 2 years old on ventilators in intensive care were included. Researchers measured heart function before, dur…

This study tested whether using ultrasound to guide a needle into the wrist artery works better than the usual method of feeling for the pulse in emergency patients with shock. One hundred adults were randomly assigned to either ultrasound guidance or the traditional palpation te…

This study looked at 300 critically ill adults in the ICU who were receiving drugs to raise their blood pressure. Researchers measured blood pressure at the upper arm and the wrist to see if there was a difference. They wanted to find out how often this difference happens and if …

This study looked at how brain blood flow and oxygen levels change when doctors treat critically ill children for shock or very low blood pressure. Researchers used a special light-based device (NIRS) and ultrasound to monitor 27 children in the intensive care unit. The goal was …