SHOCK

This study looks at whether feeding through the gut (enteral nutrition) or through a vein (parenteral nutrition) leads to better outcomes for critically ill adults recovering from shock in the ICU. About 1,150 patients will be randomly assigned to one of the two feeding methods. …

This study tests whether a simple bedside ultrasound of the inferior vena cava can detect low blood volume in shock patients as accurately as the standard invasive central venous pressure monitoring. Researchers will enroll 80 adults with shock from blood loss, infection, or othe…

This study tests a new approach for treating shock, a life-threatening condition where blood pressure drops dangerously low. Researchers will use low-intensity ultrasound on the neck to see if it can quickly raise blood pressure in 30 adult patients with mild to moderate shock. T…

This study looks at whether tissue perfusion pressure (TPP) can predict how shock patients will respond to fluids. Researchers will give a standard fluid challenge to 34 ICU patients and measure changes in TPP and cardiac output. The goal is to see if TPP is a useful tool for gui…

This study tests a non-invasive decision support system called CRUISE that helps medics identify and manage shock in critically ill adults during helicopter transport. Researchers will compare the system's recommendations to standard care given by paramedics. The goal is to see i…

This study will observe 60 adult liver transplant patients in the ICU to understand why some develop dangerous blood flow instability. Researchers will measure heart function, blood vessel tone, and oxygen delivery to tissues. The goal is to identify different patterns of instabi…

This study will test a new, non-invasive method called EIT Pulse Wave to measure blood flow to the lungs and predict heart stroke volume in critically ill patients. Researchers will compare it to the standard Swan-Ganz catheter, which is invasive. The study involves 19 adults in …

This study tests whether an AI model (ChatGPT-5) can help doctors make better decisions for critically ill patients in the intensive care unit (ICU). About 1000 adults admitted to the ICU will be randomly assigned to standard care or care where the AI provides diagnostic and trea…

This study looks at how well different veins collapse in people with severe injuries and low blood volume (shock). Researchers will use ultrasound to measure collapse of veins in the leg, neck, and belly before and after giving fluids. The goal is to see if these measurements can…

This study will test a computer model called iCVS that uses blood pressure readings to help doctors figure out why a patient is in shock. Researchers will look at data from 1,150 adults in the ICU. The goal is to see if the model can detect early warning signs and correctly class…