SHOCK

This study aims to find out if using the blood pressure drugs phenylephrine and vasopressin is better than the standard drugs norepinephrine and epinephrine for adults in the ICU with shock. The main goal is to see if the new drug combination causes fewer dangerous fast heart rhy…

This study is testing if a personalized approach to giving fluids is safer and more effective than the standard one-size-fits-all method for treating sepsis in the emergency room. Sepsis is a life-threatening reaction to infection that requires rapid treatment. Researchers will c…

This study is testing a new, simpler ultrasound measurement to see if it can quickly tell whether a patient in shock will benefit from receiving IV fluids. Doctors will use a special ultrasound scan on the heart before and after giving fluids to 187 emergency room patients. The g…

This study aims to see if using a special, focused ultrasound of the heart is safe and helpful for guiding treatment of critically ill patients in the emergency room or intensive care unit. It will enroll 1,000 adult patients who are in shock or cardiac arrest and are already sch…

This study aims to see if a protein in the blood called Vasn can help doctors better diagnose septic shock, a life-threatening infection complication. Researchers will compare Vasn levels in 144 ICU patients with septic shock to those with other types of shock. The goal is to fin…

This study aims to understand why people who survive a serious illness in the Intensive Care Unit (ICU) often have long-lasting muscle weakness and trouble exercising. Researchers will measure heart and lung fitness, as well as blood flow in the muscles, in 50 ICU survivors at 6 …

This study aims to understand if tiny particles in a premature baby's umbilical cord blood can serve as early warning signs for severe health problems. Researchers will collect cord blood from 30 infants born before 28 weeks and analyze these particles to see if they correlate wi…

This study aims to understand how often blood pressure readings from the wrist artery differ significantly from readings taken from the groin artery in patients with severe shock. Researchers will monitor 180 critically ill patients who already have both types of monitoring cathe…

This study compares two techniques for placing central venous catheters (large IVs) in emergency patients. Researchers want to see if using a small peripheral IV catheter first leads to fewer attempts, fewer complications, and faster placement than the standard needle method. The…