One-Size-Fits-All sepsis care challenged: new study tests tailored fluids

NCT ID NCT07009665

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving fluids and blood pressure medicines based on each patient's heart response can improve sepsis care. 188 adults with sepsis in the emergency department will be randomly assigned to either personalized treatment or standard care. The goal is to see if the personalized approach uses less fluid, starts medicines earlier, and leads to safer recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IV fluids and vasopressors

What this could lead to

If successful, this could lead to safer, more effective sepsis treatment by tailoring fluids to each patient's heart response, reducing complications like fluid overload.

What could go wrong

This is a small, early-phase study (188 participants) at one hospital. The personalized approach may not improve outcomes or could be harder to implement in busy ERs.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Sepsis Shock

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • University Medical Centre Groningen

    RECRUITING

    Groningen, Provincie Groningen, 9713GZ, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••