SHOCK

This study tested whether giving high doses of vitamin C through an IV to severely burned patients could prevent organ failure and death. About 666 adults with deep burns covering at least 20% of their body were to receive either vitamin C or a placebo, alongside standard care. T…

This study tests whether giving sodium bicarbonate (baking soda) to adults in the intensive care unit with metabolic acidosis can reduce the risk of major kidney problems or death within 30 days. The trial involves 500 participants who will receive either sodium bicarbonate or a …

This study tests whether giving the steroid hydrocortisone early, right when shock is diagnosed, helps very small preterm babies (under 1500 grams) recover faster. Researchers will compare babies who get standard shock treatment plus hydrocortisone to those who get standard treat…

This study tests whether increasing the backup pacing rate from 75 to 100 beats per minute improves blood flow in adults with cardiogenic shock who already have a permanent pacemaker. Twenty-five participants in the cardiac ICU will be exposed to both rates in random order, with …

This study looks at whether measuring lactate in stool can help doctors predict how well critically ill patients with low blood flow will respond to treatment. About 40 adults in the ICU will provide a stool sample within 24 hours of admission. Researchers will check if high stoo…

This study gathers 35-50 international critical care experts to agree on how to classify and manage septic shock using point-of-care ultrasound. The goal is to create consensus statements that could help personalize treatment. No patients are enrolled; instead, experts complete s…

This study looks at a new, hands-free ultrasound method to check how well shock patients tolerate fluids, using a standard score as a reference. It involves 45 adults in the ICU with shock. The goal is to see if this simpler method matches current techniques and helps predict pat…

This study tests a new digital platform that helps doctors and nurses share important patient information when a person is moved from one hospital to another. About 1,000 adults being transferred to a major hospital will take part. The goal is to see if better information sharing…