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Can baking soda save kidneys in ICU shock patients?

NCT ID NCT05697770

Ongoing Disease control Sponsor: Australian and New Zealand Intensive Care Research Centre Source: ClinicalTrials.gov ↗

First seen Jan 10, 2026 · Last updated May 15, 2026 · Updated 24 times

Summary

This study looks at whether giving sodium bicarbonate (a common acid neutralizer) to adults in the intensive care unit with metabolic acidosis and shock can prevent serious kidney problems or death within 30 days. About 500 participants receive either the bicarbonate or a placebo (sugar water) through an IV. The goal is to see if this simple treatment reduces the need for dialysis or kidney damage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Auckland City Hospital (CVICU)

    Auckland, Auckland, 1023, New Zealand

  • Auckland City Hospital (DCCM)

    Auckland, Auckland, 1023, New Zealand

  • Bendigo Hospital

    Bendigo, Victoria, 3550, Australia

  • Bunbury Regional Hospital

    Bunbury, Western Australia, 6230, Australia

  • Cairns Hospital

    Cairns, Queensland, 4870, Australia

  • Calvary Mater Newcastle

    Waratah, New South Wales, 2298, Australia

  • Canberra Hospital

    Garran, Australian Capital Territory, 2605, Australia

  • Casey Hospital

    Berwick, Victoria, 3806, Australia

  • Centro de Estudos e de Pesquisas em Terapia Intensiva

    Curitiba, Paraná, 82530-200, Brazil

  • Christchurch Hospital

    Christchurch, Christchurch, 4710, New Zealand

  • Dandenong Hospital

    Dandenong, Victoria, 3175, Australia

  • Deep Hospital

    Ludhiana, Punjab, 141002, India

  • Dunedin Hospital

    Dunedin, Dunedin, 9016, New Zealand

  • Epworth

    Richmond, Victoria, 3121, Australia

  • Flinders Medical Centre

    Bedford Park, South Australia, Australia

  • Footscray Hospital

    Footscray, Victoria, 3011, Australia

  • Frankston Hospital

    Frankston, Victoria, 3199, Australia

  • Gold Coast University Hospital

    Southport, Queensland, 4215, Australia

  • Gosford Hospital

    Gosford, New South Wales, 2250, Australia

  • Grapmians Health

    Ballarat, Victoria, 3350, Australia

  • Ipswich Hospital

    Ipswich, Queensland, 4305, Australia

  • Jawaharlal Institute of Postgraduate Medical Education and Research

    Puducherry, Puducherry, 605006, India

  • King Abdullah International Medical Research Center

    Riyadh, Riyadh Region, 11481, Saudi Arabia

  • Lyell McEwin Hospital

    Elizabeth Vale, South Australia, 5112, Australia

  • Mater Hospital

    South Brisbane, Queensland, 4101, Australia

  • Middlemore Hospital

    Auckland, Auckland, 2025, New Zealand

  • Monash Medical Centre

    Clayton, Victoria, 3168, Australia

  • Nepean Hospital

    Kingswood, New South Wales, 2747, Australia

  • Orange Health Service

    Orange, New South Wales, 2800, Australia

  • Peninsula Private Hospital

    Langwarrin, Victoria, 3910, Australia

  • Princess Alexandra Hopsital

    Woolloongabba, Queensland, 4102, Australia

  • Queen Elizabeth II Jubilee Hospital

    Coopers Plains, Queensland, 4108, Australia

  • Rotorua Hospital

    Rotorua, Rotorua, 3010, New Zealand

  • Royal Adelaide Hospital

    Adelaide, South Australia, 5000, Australia

  • Royal Brisbane and Women's Hospital

    Herston, Queensland, 4006, Australia

  • Royal Darwin Hospital

    Tiwi, Northern Territory, 0810, Australia

  • Royal North Shore Hospital

    Saint Leonards, New South Wales, 2065, Australia

  • Royal Perth Hospital

    Perth, Western Australia, 6000, Australia

  • Royal Prince Alfred Hospital

    Camperdown, New South Wales, 2050, Australia

  • St Vincent's Hospital Sydney

    Darlinghurst, New South Wales, 2010, Australia

  • St. Vincent's Hospital Melbourne

    Fitzroy, Victoria, 3065, Australia

  • Sultan Qaboos Comprehensive Cancer Care and Research Center

    Seeb, Oman

  • Sunshine Coast University Hospital

    Birtinya, Queensland, 4575, Australia

  • Sunshine Hospital

    St Albans, Victoria, 3021, Australia

  • Sutherland Hospital

    Caringbah, New South Wales, 2229, Australia

  • Sydney Adventist Hospital

    Wahroonga, New South Wales, 2076, Australia

  • The Alfred Hospital

    Melbourne, Victoria, 3004, Australia

  • The Austin Hospital

    Heidelberg, Victoria, 3084, Australia

  • The Jikei University Hospital

    Minato, Tokyo, 105-0003, Japan

  • The Queen Elizabeth Hospital

    Woodville, South Australia, 5011, Australia

  • The Victorian Heart Hospital

    Clayton, Victoria, 3065, Australia

  • Townsville University Hospital

    Douglas, Queensland, 4814, Australia

  • University Hospital Geelong

    Geelong, Victoria, 3220, Australia

  • Waikato Hospital

    Hamilton, Hamilton, 3204, New Zealand

  • Wellington Regional Hospital

    Wellington, New Zealand

Conditions

Explore the condition pages connected to this study.

METABOLIC ACIDOSIS SHOCK