POSTTRAUMATIC STRESS DISORDER

This study is testing whether a non-invasive brain stimulation technique can help people with PTSD feel calmer and learn better during therapy. Researchers will use a magnetic device to stimulate a specific brain area in 120 adults with PTSD, comparing it to a fake stimulation. T…

This study is testing a new talk therapy that combines two proven treatments—one for PTSD and one for alcohol use—to see if it works better than the alcohol treatment alone. It will involve 200 adults who struggle with both conditions. Researchers will measure changes in drinking…

This small pilot study is testing whether a standard talk therapy for PTSD (Cognitive Processing Therapy) can reduce the risk of heart disease in people with both PTSD and heart risk factors. Researchers will measure changes in brain activity, body-wide inflammation, and nervous …

This study is testing whether giving two psychedelic substances, MDMA and psilocybin, together is safe and might help reduce PTSD symptoms in military Veterans. Researchers at Johns Hopkins will give the combined treatment during two therapy sessions to 40 Veterans with long-term…

This study is testing whether a mobile app called 'PE Coach' helps veterans with PTSD get more out of their therapy. 124 veterans will receive a proven talk therapy, with half also using the app for homework support. Researchers will check if the app helps people stick with treat…

This study is testing a 12-week talk therapy program for people with PTSD. Participants will be randomly assigned to receive either this new therapy or their usual care. Researchers will track symptoms, sleep, anxiety, and depression for a full year to see if the therapy provides…

This study is testing a step-by-step support program called TRRP to help people get mental health care after a serious physical injury. It will involve 350 patients at a Washington D.C. hospital who are at risk for PTSD or depression. The program provides education, check-ins via…

This study aims to help veterans with PTSD who aren't improving with their first treatment. Researchers will test whether switching to a different therapy approach or using text message reminders for homework assignments works better. The goal is to find the right treatment combi…

This study is testing a combined therapy program that addresses both anxiety disorders and alcohol use at the same time for military veterans. The program aims to help 40 veterans improve their daily functioning, social relationships, and overall quality of life. Researchers want…

This study is testing a smartphone-based therapy app designed to prevent post-traumatic stress disorder (PTSD) and problematic cannabis use in women who have recently experienced sexual assault. The app focuses on reducing anxiety sensitivity, a known risk factor for these condit…

This study is testing whether a brief, three-session therapy can prevent posttraumatic stress disorder (PTSD) in people who have been seriously injured. Researchers will enroll 300 patients admitted to Level 1 trauma centers and randomly assign them to receive either the brief th…

This study is testing if a short, intensive form of talk therapy (cognitive behavioral therapy) can better help veterans and service members with PTSD and anxiety disorders. Researchers are comparing two delivery methods—individual sessions over two weeks versus group sessions ov…

This study tests whether involving family members in PTSD therapy helps Veterans stick with treatment and get better results. Veterans starting standard PTSD therapy will have their family members randomly assigned to receive either a brief 2-session family support program or no …

This small pilot study is testing whether virtual reality therapy can help reduce PTSD symptoms in healthcare workers and COVID-19 patients. Participants will use VR headsets during therapy sessions to safely revisit traumatic experiences. The study aims to see if this approach i…

This pilot study is testing whether a flexible, stepped care program is a practical and acceptable way to help people who have both chronic pain and PTSD. Researchers will compare this new approach to usual care in two primary care clinics. The main goal is to see if the program …

This study is testing if a drug (ketamine) or a nerve-blocking injection (stellate ganglion block), alone or together, can reduce headaches and PTSD symptoms in people with traumatic brain injury (TBI). It will involve 175 adults who have had these conditions for over 3 months. T…

This study is testing whether a brief writing therapy can help veterans who are dealing with both post-traumatic stress disorder (PTSD) and substance use problems. Veterans in standard addiction treatment will be randomly assigned to either write about a traumatic experience or a…

This study is testing a mobile phone app designed to help veterans with PTSD manage anger problems. Researchers will compare the anger management app to a general health education app in 150 veterans. The goal is to see if the specialized app is better at reducing anger and impro…

This study aims to understand how art therapy helps military personnel manage post-traumatic stress symptoms. Researchers will work with 40 active-duty or recently separated veterans who experience significant PTSD symptoms. Participants will attend art therapy sessions and have …

This research aims to better understand how heavy drinking and post-traumatic stress disorder (PTSD) together might influence conflict and aggression between partners. The study will observe 70 couples, some with PTSD, in both a controlled lab setting and their daily lives over 2…