POSTTRAUMATIC STRESS DISORDER
Clinical trials for POSTTRAUMATIC STRESS DISORDER explained in plain language.
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New approach aims to help veterans with PTSD reclaim their lives
Disease control CompletedThis study tested a personalized version of a standard talk therapy for PTSD, called Cognitive Processing Therapy (CPT). It involved 179 Veterans and aimed to see if tailoring the therapy to address each person's specific life challenges—like work, relationships, or other stresso…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New therapy aims to break cycle of drinking and trauma for veterans
Disease control CompletedThis study tested a therapy called Behavioral Activation, adapted for veterans struggling with both alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD). It compared this approach to a standard relapse prevention treatment. The goal was to see if helping veterans e…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: RTI International • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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Neck injection could boost PTSD therapy success
Disease control CompletedThis study tested if adding a simple neck injection to a standard PTSD therapy could make the therapy work better. Researchers compared the standard therapy alone to the therapy combined with either a real or a fake (placebo) injection. The goal was to see if the combination coul…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Sleep therapy may shield PTSD hearts
Disease control CompletedThis study investigated whether treating insomnia could reduce the higher risk of heart disease seen in people with PTSD. Researchers enrolled 140 adults with both PTSD and insomnia. They tested if an 8-week sleep therapy program could improve key markers of heart health, like bl…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Kenya trial finds path to mental health care where specialists are scarce
Disease control CompletedThis study tested two different treatments for depression and trauma-related disorders that could be delivered by trained non-specialists in Kenya, where mental health professionals are scarce. Over 2,100 primary care patients received either talk therapy or medication as a first…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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Brain wave therapy tested as new PTSD treatment
Disease control CompletedThis study tested whether a personalized magnetic brain stimulation therapy could help reduce symptoms of Post-Traumatic Stress Disorder (PTSD). 158 adults with PTSD received either the real treatment or a placebo version for 5 weeks, with neither participants nor doctors knowing…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Wave Neuroscience • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New text & video program aims to shield assault survivors from PTSD and opioid misuse
Prevention CompletedThis study tested a new support program for adults who recently experienced sexual assault. Researchers developed a brief video to watch during a medical exam and follow-up text messages for the next month. The goal was to see if this approach could help prevent the development o…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Prevention
Last updated Mar 16, 2026 15:24 UTC
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Can training a service dog heal invisible wounds? military study investigates
Symptom relief CompletedThis study looked at whether learning to train a future service dog, combined with standard medical care, could help reduce symptoms of post-traumatic stress (PTS) and post-concussive symptoms in military members. Researchers enrolled 156 participants to measure changes in stress…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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VA study tests One-Size-Fits-All therapy against standard treatments
Symptom relief CompletedThis study compared two types of talk therapy for veterans with PTSD, depression, or panic disorder. Researchers tested if a single, streamlined therapy could work as well as separate, disorder-specific therapies. 304 veterans received 12 weeks of either the new combined approach…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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New hope for healing trauma after spinal cord injury
Symptom relief CompletedThis study tested whether a specific talk therapy called Prolonged Exposure Therapy could help reduce symptoms of post-traumatic stress disorder (PTSD) in people living with spinal cord injuries. 30 participants were randomly assigned to receive either this therapy or continue wi…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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New hope for Veterans' PTSD brain fog: training program shows promise
Symptom relief CompletedThis small pilot study tested whether a thinking skills training program could help veterans with PTSD who still struggle with memory, focus, and concentration after standard PTSD therapy. Researchers worked with 21 veterans to see if the training was practical and acceptable, an…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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New hope for Veterans' PTSD? brain hormone tested in groundbreaking trial
Symptom relief CompletedThis study tested whether a medication called pregnenolone could help reduce symptoms of PTSD in veterans from the Iraq and Afghanistan wars. For 10 weeks, 96 veterans with PTSD received either the real medication or a placebo pill, without knowing which one. Researchers measured…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: PHASE2 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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New program aims to help pregnant moms and their babies after violence
Symptom relief CompletedThis study tested a special support program for pregnant women who have recently experienced violence from a partner. The program aimed to help improve the mothers' mental health, reduce their risk of further violence, and support better parenting and infant development. Research…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: University of Notre Dame • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Healing the hidden wounds: new app aims to mend minds after childhood trauma
Symptom relief CompletedThis study tested a new mobile app called CAARE, designed to help children and their parents cope with the emotional stress that often follows a serious injury. It involved 54 families where a child under 12 was hospitalized for an injury. The goal was to see if using the app cou…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Mar 23, 2026 15:18 UTC
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Video game therapy eases Mothers' traumatic birth flashbacks
Symptom relief CompletedThis study tested whether a single therapy session could reduce traumatic memories after childbirth. Mothers who experienced distressing flashbacks played the game Tetris after briefly recalling their birth experience. Researchers compared 120 women who received immediate treatme…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Centre Hospitalier Universitaire Vaudois • Aim: Symptom relief
Last updated Mar 16, 2026 15:24 UTC
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Could sensory differences predict PTSD in soldiers?
Knowledge-focused CompletedThis study investigated whether having sensory processing differences makes a person more vulnerable to developing PTSD symptoms after experiencing trauma. Researchers showed combat-related movie clips to 248 healthy young adults, some with and some without sensory issues, and me…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Tel Aviv University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC