POSTPARTUM DEPRESSION

This study tested a program called the Pregnant Moms' Empowerment Program (PMEP) for pregnant women who had experienced intimate partner violence in the past year. About 230 women took part in either the PMEP or a general discussion group during pregnancy. The goal was to see if …

This study looked at how a type of therapy called Mindfulness-Based Cognitive Therapy (MBCT) helps pregnant women who are feeling stressed, anxious, or down. 84 at-risk pregnant women took part to see if MBCT could boost their well-being during pregnancy and after giving birth. T…

This study looked at ways to reduce pain in women who had severe tears (called OASIS) during childbirth. 67 women received either a placebo, a low dose of ketamine plus morphine, or morphine alone through an epidural. The goal was to see which option worked best for pain one week…

This study tested whether a single injection of RE104 can safely reduce depression symptoms in 84 women with moderate-to-severe postpartum depression. Participants received either a higher or lower dose, and researchers measured changes in depression scores over time. The goal is…

This study tested a new medicine called SAGE-547 in 138 women with severe postpartum depression. The medicine was given as a 60-hour IV drip to see if it could quickly reduce depression symptoms compared to a placebo. The goal was to help new mothers feel better within days, not …

This study tested whether a 12-session parenting group therapy, called the Connecting and Reflecting Experience (CARE) program, is helpful and doable for new parents experiencing postpartum depression or anxiety. Seventeen parents with infants aged 3 to 12 months took part. The g…

This study tested an experimental oral drug called NORA520 in 93 women with severe postpartum depression. Participants took the drug or a placebo for 3 days to see if it safely reduces depressive symptoms. The goal is to find a fast-acting, well-tolerated treatment for new mother…

This study tested a non-drug treatment called Personalized Integrated Chronotherapy (PIC) for depression during pregnancy and after childbirth. 120 pregnant women with major depression received either usual care (medication or therapy) or PIC plus usual care. PIC combines bright …

This study tested a medicine called SAGE-547 given as a 60-hour IV drip to women with moderate or severe postpartum depression. 108 women took part. The goal was to see if it could quickly reduce depression symptoms compared to a placebo. Results showed improvement in depression …

This early study tested an experimental drug called SAGE-547 in 4 women with severe postpartum depression. The main goal was to see if the injection was safe and how the body processed it. Researchers also looked for signs that symptoms improved, but the study was too small to dr…

This study looked at whether the drug ZULRESSO (brexanolone) can be safely given to women with postpartum depression in their own homes instead of a clinic. Fifty-two women took part, and researchers tracked side effects and whether the safety rules were followed. The goal was to…

This study tested a special educational program to help new mothers reduce feelings of depression and build a stronger connection with their babies. The program was based on the Watson Human Caring Model, which focuses on caring and personal support. 88 pregnant women took part, …

This study tested whether adding psychodramatic role-playing to standard childbirth preparation classes could reduce postpartum depression and improve self-efficacy and social support in first-time mothers. 57 pregnant women participated, with one group receiving standard educati…

This study tested whether a virtual group session for Spanish-speaking mothers of newborns could help them learn about postpartum depression and connect with support resources. 26 mothers participated in a single online session during a well-child visit. The goal was to see if th…

This study tested a free chatbot named Rosie that answers moms' questions about pregnancy, baby health, and postpartum depression. It uses information from trusted sources like children's hospitals and government agencies, and works in English and Spanish. The study included 400 …

This study looked at whether the sudden drop in pregnancy hormones or the long exposure to them causes mood problems after childbirth. 74 women with a history of postpartum depression took part. Researchers measured their mood using a standard questionnaire to understand the link…

This study followed 300 pregnant women, some with a history of mood disorders and some without, to understand why some develop depression or other mood problems after giving birth. Researchers collected blood samples and tracked sleep, stress, and other factors to find genetic, h…

This study tested a program to help Black mothers after childbirth who are at high risk for health problems. Participants received a helpful pamphlet and a patient navigator they could contact for 30 days. The goal was to see if this support reduces emergency room visits and help…