POSTPARTUM DEPRESSION

This study tested a new oral medication called NORA520 as a potential treatment for severe postpartum depression. It involved 93 women who were randomly assigned to receive either the drug or a placebo for 3 days. Researchers measured how well it reduced depression symptoms, its …

This study tested whether adding a non-drug treatment to standard care could better help pregnant women and new mothers with depression. The treatment involved using a bright light box each morning and following a personalized sleep schedule. Researchers compared this combined ap…

This study tested whether a 60-hour IV treatment for postpartum depression could be safely given at home instead of in a hospital. It involved 52 women and carefully monitored for safety issues and whether healthcare providers could follow all the required safety steps in a home …

This study tested whether extra support could help new mothers at highest risk avoid emergency room visits and get better access to care in their first month after delivery. Researchers enrolled 220 Black women who had just given birth and were identified as high-risk. Half recei…

This study tested whether virtual group sessions during pediatric visits could help Spanish-speaking mothers learn about postpartum depression and connect with support resources. Researchers worked with 26 mothers of infants to provide education about depression symptoms, reduce …

This study tested whether a special support program could help new mothers. The program involved six one-on-one conversations based on caring principles, aiming to reduce feelings of depression after birth and help mothers feel closer to their babies. It compared mothers who rece…

This small, early study tested the safety and initial effects of an experimental injection called SAGE-547 for severe postpartum depression. Four adult women with severe depression after childbirth received the treatment. Researchers closely monitored their health and checked if …

This study tested whether a mindfulness-based therapy program could help reduce psychological distress in pregnant women at risk for depression and anxiety. It involved 84 pregnant women in the U.S. who reported feeling distressed. The main goal was to see if the therapy improved…

This completed Phase 3 trial tested whether a 60-hour intravenous infusion of an experimental drug, SAGE-547, could reduce depressive symptoms in women with moderate to severe postpartum depression. The study involved 108 women who were within six months of giving birth and compa…

This study tested different pain relief methods for women who experienced severe tears during childbirth. It involved 67 women who received either a placebo, a low-dose ketamine and morphine combination, or morphine alone shortly after delivery. The goal was to see which method b…

This study tested whether a 12-session parenting group therapy program is helpful and practical for new parents experiencing postpartum depression or anxiety. The program, called CARE, focuses on helping parents understand their own and their baby's feelings to improve their rela…

This study tested whether a 60-hour intravenous infusion of an experimental drug called SAGE-547 could reduce severe depressive symptoms in women with postpartum depression. It involved 138 women who were within 6 months of giving birth and had severe symptoms. The main goal was …

This study tested a special support program for pregnant women who have recently experienced violence from a partner. The program aimed to help improve the mothers' mental health, reduce their risk of further violence, and support better parenting and infant development. Research…

This study aimed to understand if sudden hormone changes after pregnancy trigger postpartum depression. Researchers gave hormones to 74 women with and without previous postpartum depression, then stopped them to mimic childbirth. They measured mood changes to see if hormone withd…

This study aimed to understand what causes mood episodes like depression after childbirth. Researchers followed 300 pregnant women, some with and some without a history of mood disorders, to track their mental health. They collected information on genes, hormones, stress, and sle…