New shot may ease postpartum depression in days

NCT ID NCT02942017

First seen Oct 31, 2025 · Last updated May 08, 2026 · Updated 31 times

Summary

This study tested a medicine called SAGE-547 given as a 60-hour IV drip to women with moderate or severe postpartum depression. 108 women took part. The goal was to see if it could quickly reduce depression symptoms compared to a placebo. Results showed improvement in depression scores at 60 hours and at 30 days.

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Contacts and locations

Locations

  • Sage Investigational Site

    Chandler, Arizona, 85226, United States

  • Sage Investigational Site

    Rogers, Arkansas, 72758, United States

  • Sage Investigational Site

    Lemon Grove, California, 91945, United States

  • Sage Investigational Site

    Orange, California, 92868, United States

  • Sage Investigational Site

    Ventura, California, 93003, United States

  • Sage Investigational Site

    Gainesville, Florida, 32607, United States

  • Sage Investigational Site

    Miami, Florida, 33147, United States

  • Sage Investigational Site

    Miramar, Florida, 33027, United States

  • Sage Investigational Site

    Orlando, Florida, 32807, United States

  • Sage Investigational Site

    Pensacola, Florida, 32502, United States

  • Sage Investigational Site

    Pinellas Park, Florida, 33782, United States

  • Sage Investigational Site

    Atlanta, Georgia, 30331, United States

  • Sage Investigational Site

    Hoffman Estates, Illinois, 60169, United States

  • Sage Investigational Site

    Wichita, Kansas, 67226, United States

  • Sage Investigational Site

    Edgewood, Kentucky, 41017, United States

  • Sage Investigational Site

    Owensboro, Kentucky, 42303, United States

  • Sage Investigational Site

    Boston, Massachusetts, 02114, United States

  • Sage Investigational Site

    Flowood, Mississippi, 39232, United States

  • Sage Investigational Site

    Marlton, New Jersey, 08053, United States

  • Sage Investigational Site

    Glen Oaks, New York, 11004, United States

  • Sage Investigational Site

    Chapel Hill, North Carolina, 27514, United States

  • Sage Investigational Site

    Charlotte, North Carolina, 28211, United States

  • Sage Investigational Site

    Raleigh, North Carolina, 27612, United States

  • Sage Investigational Site

    Columbus, Ohio, 43210, United States

  • Sage Investigational Site

    Dayton, Ohio, 45417, United States

  • Sage Investigational Site

    Philadelphia, Pennsylvania, 19104, United States

  • Sage Investigational Site

    Baytown, Texas, 77521, United States

  • Sage Investigational Site

    Houston, Texas, 77030, United States

  • Sage Investigational Site

    Houston, Texas, 77058, United States

  • Sage Investigational Site

    Richardson, Texas, 75080, United States

  • Sage Investigational Site

    San Antonio, Texas, 78229, United States

  • Sage Investigational Site

    Orem, Utah, 84058, United States

Conditions

Explore the condition pages connected to this study.