Single shot could lift postpartum depression, early trial hints

NCT ID NCT06342310

Completed Symptom relief Sponsor: Reunion Neuroscience Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a single injection of RE104 in 84 women with moderate-to-severe postpartum depression. The goal was to see if it reduces depressive symptoms better than a low-dose comparison. Results will help determine if this approach is safe and effective for new mothers.

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Conditions

The condition(s) this trial relates to.

postpartum depression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTPARTUM DEPRESSION

Contacts and locations

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Locations

Reunion Investigational Site

Santa Monica, California, 90404, United States
Reunion Investigational Site

Boulder, Colorado, 80045, United States
Reunion Investigational Site

Denver, Colorado, 80209, United States
Reunion Investigational Site

Lauderhill, Florida, 33319, United States
Reunion Investigational Site

Tampa, Florida, 33613, United States
Reunion Investigational Site

Birmingham, Alabama, 35209, United States
Reunion Investigational Site

Tucson, Arizona, 85724, United States
Reunion Investigational Site

Atlanta, Georgia, 30329, United States
Reunion Investigational Site

Atlanta, Georgia, 30331, United States
Reunion Investigational Site

Decatur, Georgia, 30030, United States
Reunion Investigational Site

Marietta, Georgia, 30060, United States
Reunion Investigational Site

Savannah, Georgia, 31405, United States
Reunion Investigational Site

Honolulu, Hawaii, 96817, United States
Reunion Investigational Site

Kansas City, Kansas, 66160, United States
Reunion Investigational Site

Shreveport, Louisiana, 71106, United States
Reunion Investigational Site

Baltimore, Maryland, 21205, United States
Reunion Investigational Site

Rockville, Maryland, 20850, United States
Reunion Investigational Site

Springfield, Massachusetts, 01103, United States
Reunion Investigational Site

Novi, Michigan, 48377, United States
Reunion Investigational Site

Albuquerque, New Mexico, 87131, United States
Reunion Investigational Site

Buffalo, New York, 14202, United States
Reunion Investigational Site

New York, New York, 10016, United States
Reunion Investigational Site

New York, New York, 10026, United States
Reunion Investigational Site

Chapel Hill, North Carolina, 27599, United States
Reunion Investigational Site

Monroe, North Carolina, 28112, United States
Reunion Investigational Site

Cleveland, Ohio, 44113, United States
Reunion Investigational Site

Columbus, Ohio, 43210, United States
Reunion Investigational Site

West Chester, Pennsylvania, 19380, United States
Reunion Investigational Site

Austin, Texas, 78712, United States
Reunion Investigational Site

Austin, Texas, 78737, United States
Reunion Investigational Site

Austin, Texas, 78759, United States
Reunion Investigational Site

Plano, Texas, 75093, United States
Reunion Investigational Site

San Antonio, Texas, 78229, United States
Reunion Investigational Site

Draper, Utah, 84020, United States
Reunion Investigational Site

Salt Lake City, Utah, 84108, United States
Reunion Investigational Site

Charlottesville, Virginia, 22903, United States
Reunion Investigational Site

Seattle, Washington, 98105, United States
Reunion Investigational Site

Madison, Wisconsin, 53719, United States