New shot shows promise for new moms battling severe depression

NCT ID NCT06342310

Completed Symptom relief Sponsor: Reunion Neuroscience Inc Source: ClinicalTrials.gov ↗

First seen May 15, 2026 · Last updated May 15, 2026

Summary

This study tested whether a single injection of RE104 can safely reduce depression symptoms in 84 women with moderate-to-severe postpartum depression. Participants received either a higher or lower dose, and researchers measured changes in depression scores over time. The goal is to find a fast-acting treatment for new mothers struggling with depression.

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Contacts and locations

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Locations

Reunion Investigational Site

Birmingham, Alabama, 35209, United States
Reunion Investigational Site

Tucson, Arizona, 85724, United States
Reunion Investigational Site

Santa Monica, California, 90404, United States
Reunion Investigational Site

Boulder, Colorado, 80045, United States
Reunion Investigational Site

Denver, Colorado, 80209, United States
Reunion Investigational Site

Lauderhill, Florida, 33319, United States
Reunion Investigational Site

Tampa, Florida, 33613, United States
Reunion Investigational Site

Atlanta, Georgia, 30329, United States
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Atlanta, Georgia, 30331, United States
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Decatur, Georgia, 30030, United States
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Marietta, Georgia, 30060, United States
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Savannah, Georgia, 31405, United States
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Honolulu, Hawaii, 96817, United States
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Kansas City, Kansas, 66160, United States
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Shreveport, Louisiana, 71106, United States
Reunion Investigational Site

Baltimore, Maryland, 21205, United States
Reunion Investigational Site

Rockville, Maryland, 20850, United States
Reunion Investigational Site

Springfield, Massachusetts, 01103, United States
Reunion Investigational Site

Novi, Michigan, 48377, United States
Reunion Investigational Site

Albuquerque, New Mexico, 87131, United States
Reunion Investigational Site

Buffalo, New York, 14202, United States
Reunion Investigational Site

New York, New York, 10016, United States
Reunion Investigational Site

New York, New York, 10026, United States
Reunion Investigational Site

Chapel Hill, North Carolina, 27599, United States
Reunion Investigational Site

Monroe, North Carolina, 28112, United States
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Cleveland, Ohio, 44113, United States
Reunion Investigational Site

Columbus, Ohio, 43210, United States
Reunion Investigational Site

West Chester, Pennsylvania, 19380, United States
Reunion Investigational Site

Austin, Texas, 78712, United States
Reunion Investigational Site

Austin, Texas, 78737, United States
Reunion Investigational Site

Austin, Texas, 78759, United States
Reunion Investigational Site

Plano, Texas, 75093, United States
Reunion Investigational Site

San Antonio, Texas, 78229, United States
Reunion Investigational Site

Draper, Utah, 84020, United States
Reunion Investigational Site

Salt Lake City, Utah, 84108, United States
Reunion Investigational Site

Charlottesville, Virginia, 22903, United States
Reunion Investigational Site

Seattle, Washington, 98105, United States
Reunion Investigational Site

Madison, Wisconsin, 53719, United States

Conditions

Explore the condition pages connected to this study.

POSTPARTUM DEPRESSION