PNEUMONIA

This study aims to see if combining a traditional Chinese herbal formula with a special virus therapy can help people with severe pneumonia caused by bacteria that don't respond to standard antibiotics. Researchers will enroll 240 adults with this hard-to-treat infection to test …

This study is testing whether adding probiotics to standard pneumonia treatment helps young children recover better. Researchers will give 330 children aged 6-36 months either a probiotic nasal spray, a spray plus an oral probiotic, or a placebo, alongside their regular hospital …

This study aims to find out if a shorter, 5-day course of antibiotics works just as well as a standard 10-day course for children hospitalized with common infections like pneumonia, skin infections, or urinary tract infections. About 1,200 children will be randomly assigned to re…

This study aims to test a new care plan to help doctors decide when antibiotics are truly needed for children with mild pneumonia. It will enroll about 700 children in emergency rooms who are well enough to go home. The goal is to safely reduce unnecessary antibiotic prescription…

This study is testing if a special low-carbohydrate, high-fat diet (ketogenic diet) is better than standard hospital food at helping older adults with pneumonia keep their muscle strength and function while they recover in the hospital. Researchers will compare the two diets in 3…

This study is testing whether an AI guidance system helps doctors perform bronchoscopy exams more accurately in patients with severe pneumonia. The system provides visual cues and voice prompts during the procedure to help locate the correct area of the lung, but doctors make all…

This study aims to see if a new, non-invasive urine test can accurately diagnose pneumonia caused by specific types of bacteria in young children in Malawi. Researchers will test 350 existing urine samples from children, comparing the new test results to standard methods. The goa…

This study is testing a device called Inflammacheck that measures chemicals in a person's breath. Researchers want to see if these breath markers can help tell the difference between lung cancer and other lung conditions like pneumonia or asthma. They will collect breath samples …

This study aims to see how well a pneumonia vaccine (PCV20) prevents lung infections in adults at higher risk. It will use existing health records from over 800,000 Kaiser Permanente members in Southern California, comparing infection rates between those who received the vaccine …

This study is testing whether adding a special percussive breathing treatment to standard care helps adults with severe pneumonia who are on a breathing machine. Researchers want to see if this extra treatment helps patients get off the ventilator sooner, improves how well their …

This study is testing if a simple breathing exercise can help young children with pneumonia. Kids aged 3-4 will practice a special blowing technique with a toy twice a day for three days. Researchers will check if it helps their breathing, heart rate, and oxygen levels, and if it…

This study aims to find the best way to keep children with pneumonia comfortable while they are on a breathing machine. It will compare two common sedation methods: a steady drip of medicine versus planned daily breaks. Researchers will measure comfort levels in about 100 childre…

This study aims to gather detailed information about Respiratory Syncytial Virus (RSV) infections in children under 5 years old in Türkiye. Researchers will observe 4,000 children who test positive for RSV when they visit pediatric emergency departments over two seasons. The goal…

This study aims to understand how often viruses like RSV, flu, and COVID-19 cause serious lung infections (pneumonia) in a rural part of India. Researchers will closely monitor 2000 children and adults in 30 villages for three years, tracking illnesses from home visits to hospita…

This study is testing if a smartphone chatbot can help family members caring for elderly pneumonia patients at home. It will compare the chatbot to standard paper instructions to see which better improves caregivers' knowledge, confidence, and caregiving skills. The goal is to fi…

This study aims to understand if patients who need an emergency breathing tube are more likely to develop pneumonia compared to those who get one in a planned, non-emergency setting. Researchers will review the medical records of 600 adults who were intubated and stayed in intens…

This study aims to understand how different pressure settings on a breathing machine affect the lungs and breathing muscles of patients in the intensive care unit. Researchers will test three pressure levels on 25 patients who are on a specific type of ventilator support. The goa…

This study aims to better understand how the breathing muscles work in ICU patients with pneumonia who are trying to come off a ventilator. Researchers will use a bedside ultrasound machine to take pictures and measurements of key breathing muscles daily during the weaning proces…