PNEUMONIA

This early-phase trial tests whether combining a traditional Chinese herbal formula (Yiqi Huoxue Jiedu) with bacteriophages (viruses that kill bacteria) can clear drug-resistant bacteria from the lungs of 240 adults with severe pneumonia. The goal is to improve recovery and lower…

This study looks at whether using lower doses of two blood thinners (argatroban and enoxaparin) can reduce bleeding and clotting problems in adults on ECMO, a machine that helps the heart and lungs. About 200 participants with pneumonia or heart failure will be enrolled. The goal…

This study tests whether a pharmacist-led electronic consultation can help people with HIV use certain lung medications and smoking-cessation aids more appropriately. About 480 participants who smoke or take certain inhalers or acid-reducing pills will receive tailored medication…

This study tests whether a ketogenic (low-carb, high-fat) diet helps older adults hospitalized with pneumonia maintain muscle function better than a standard hospital diet. Researchers will enroll 30 patients aged 55 and older and track safety, diet adherence, and handgrip streng…

This study tests a new AI system that helps doctors perform bronchoscopy (a procedure to look inside the lungs) in 100 adults with severe pneumonia. The AI provides real-time visual and voice guidance to locate the right lung areas and describe findings, but doctors make all deci…

This study aims to see if a simple urine test can accurately diagnose pneumococcal pneumonia in children under 5 in Malawi, where the disease is a leading cause of death. Researchers will test 350 stored urine samples from healthy children and those with pneumonia, comparing resu…

This study aims to improve how doctors diagnose severe lung infections in children. It will look at 50 children in intensive care to see if measuring the body's immune response, along with advanced bug detection, can tell which germ is actually causing the illness. The goal is to…

This study tests whether using a high-flow nasal cannula (a device that delivers warm, moist oxygen at high speeds) for 24 hours right after major abdominal surgery can prevent early lung complications like pneumonia or collapsed lungs. About 580 adults having long abdominal surg…

This study tests four different nebulized liquids (salt water at various strengths and distilled water) to see which helps pneumonia patients clear mucus from their lungs most effectively. Eighty adults with pneumonia who need help coughing up phlegm will receive treatment four t…

This study tests whether a simple breathing exercise called pursed-lip breathing can help children ages 3 to 4 with pneumonia breathe better and get ready to leave the hospital sooner. About 66 children will practice the exercise twice a day for three days while in the hospital. …

This study tests whether adding probiotic nasal spray and oral probiotics to standard pneumonia treatment helps children aged 6 to 36 months recover faster. About 330 hospitalized children will be split into three groups: one gets a placebo, one gets a probiotic nasal spray, and …

This study tests whether a high-flow nasal cannula (a device that delivers warm, humidified oxygen) can prevent dangerously low oxygen levels in children aged 1 to 6 years during a sedated bronchoscopy (a procedure to look inside the lungs). About 430 children will be randomly as…

This study looks at two ways to give sedation medicine to children aged 5-10 who are on breathing machines for pneumonia. One method gives medicine continuously, the other pauses it daily. The goal is to see which approach keeps children more comfortable and safe. About 96 childr…

This study will observe 4,000 children under 5 who test positive for RSV and visit pediatric emergency rooms in Turkey. Researchers want to learn how many need hospital care, breathing support, or ICU admission. The goal is to better understand the virus's impact and help hospita…

This study looks at how different levels of pressure from a breathing machine (ventilator) affect the lungs and diaphragm in 25 ICU patients with respiratory failure. Each patient will try three pressure settings to see which one helps them breathe more efficiently and with less …

This study will review the medical records of 500 adults hospitalized with pneumonia between 2023 and 2026. Researchers aim to identify common symptoms, causes, and factors that influence recovery. No new treatments or drugs are given; the goal is to learn from past patient data …

This study looks at 150 ICU patients with pneumonia who are on breathing machines. Doctors will use bedside ultrasound to measure the thickness and movement of key breathing muscles (diaphragm and others) during the process of taking patients off the ventilator. The goal is to se…

This study looks at whether patients who get a breathing tube in an emergency are more likely to develop pneumonia than those who get one in a planned setting. Researchers will review medical records of 600 adults intubated in 2024. The goal is to understand how urgency affects i…

This study will follow 2,000 people—children under 5 and adults aged 16-60—in 30 villages in rural India to track how often they get serious lung infections like RSV, flu, and COVID-19. Researchers will visit homes weekly and test samples to measure how many people get sick, need…

This study will follow about 2,700 adults with pneumonia to learn why some people get much sicker while others recover. Researchers will track patients from the start of their illness through recovery, using medical tests and health records. The goal is to find better ways to pre…

This study tests a chatbot called 'Pneumonia Care Helper' to see if it helps caregivers of elderly pneumonia patients learn more than traditional paper handouts. About 150 caregivers will use either the chatbot or paper instructions for 5 days. The goal is to see if the chatbot i…