PERIODONTAL DISEASES
Clinical trials for PERIODONTAL DISEASES explained in plain language.
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New gum surgery showdown: which technique heals better?
Disease control Recruiting nowThis study compares three surgical techniques for treating gum disease (periodontitis). The goal is to see which method best reduces deep gum pockets and helps gums reattach to teeth. About 60 adults with periodontitis will be enrolled. The results will help dentists choose the m…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Universidad de Murcia • Aim: Disease control
Last updated May 01, 2026 16:00 UTC
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Gum disease gel shows promise in early trial
Disease control Recruiting nowThis study tests whether a gel containing lovastatin, placed under the gum after deep cleaning, can improve gum health better than cleaning alone. It includes 44 adults with periodontitis, both smokers and non-smokers, and compares treated and untreated teeth in the same person o…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Medical University of Silesia • Aim: Disease control
Last updated May 01, 2026 15:59 UTC
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Gum bone repair showdown: new collagen matrix takes on standard bone graft
Disease control Recruiting nowThis study tests whether a new collagen material can help regrow bone lost to gum disease as well as the current standard treatment (a bone mineral graft). About 80 adults with advanced periodontitis will receive one of the two treatments during surgery. Researchers will measure …
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: University of Bern • Aim: Disease control
Last updated May 01, 2026 15:58 UTC
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New gum surgery technique aims to save healing tissue
Disease control Recruiting nowThis study compares a new, less invasive surgical method for treating advanced gum disease to the standard approach. The new method uses a single incision to preserve blood supply and keep granulation tissue (which helps healing) in place. Fifty adults with deep gum pockets that …
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Universidad de Murcia • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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New study tests virtual dental coaching for cancer survivors
Disease control Recruiting nowThis study tests whether a telehealth program can help cancer survivors prevent mouth sores, gum disease, and tooth decay, and improve their quality of life. Researchers will enroll 100 cancer survivors who finished primary treatment at least 6 months ago. Participants will eithe…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Georgetown University • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Could a blood protein boost bone healing in gum disease?
Disease control Recruiting nowThis study tests whether adding injectable platelet-rich fibrin (i-PRF) to a standard bone graft helps repair deep gum defects caused by periodontitis. Sixteen adults with stage III gum disease will receive either the combination treatment or the graft alone. The goal is to see i…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Saglik Bilimleri Universitesi • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Microscope magic? new study tests Super-Magnified gum surgery for faster healing
Symptom relief Recruiting nowThis study tests whether using a microscope during gum surgery helps the gums heal better than using standard magnifying glasses (dental loupes). About 25 adults with gum disease will take part. The main goal is to see if the microscope leads to faster and better wound healing.
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Symptom relief
Last updated May 01, 2026 15:59 UTC
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Gum health linked to rare skin disease severity in new study
Knowledge-focused Recruiting nowThis study looks at how the severity of pemphigus vulgaris, a chronic autoimmune skin disease, relates to gum health. Researchers will measure mouth sores and blood markers in 20 adults and compare them with dental exams. The goal is to understand if worse disease leads to worse …
Matched conditions: PERIODONTAL DISEASES
Sponsor: Saglik Bilimleri Universitesi • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Blood and saliva clues may predict gum healing success
Knowledge-focused Recruiting nowThis study looks at whether certain markers in blood and saliva can help predict how well people with gum disease will heal after non-surgical treatment. Researchers will measure these markers in 180 adults (healthy, with gingivitis, or with advanced periodontitis) before and aft…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Ömer Faruk Okumuş • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC
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Scientists probe immune pathway in gum disease for future treatments
Knowledge-focused Recruiting nowThis observational study aims to understand whether a specific immune pathway (JAK1/2) is overactive in people with gum disease (periodontitis) compared to those with healthy gums. Researchers will collect gum tissue from 30 adults to measure pathway activation. Findings could le…
Matched conditions: PERIODONTAL DISEASES
Sponsor: University of Chile • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:14 UTC
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Scientists dig into gum tissue to uncover healing secrets
Knowledge-focused Recruiting nowThis study looks at gum tissue from people with severe gum disease to understand how it heals and fights infection. Researchers will compare tissue from above and below the gum line, and also see if smoking affects healing. 46 adults with advanced periodontitis will provide sampl…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Riga Stradins University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC
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EVALUATION OF THE EFFECT OF INDIVIDUALS' ORAL HYGIENE HABITS AND PERIODONTAL STATUS ON QUALITY OF LIFE
Recruiting nowThis cross-sectional study aims to evaluate the relationship between oral hygiene habits, periodontal status, and oral health-related quality of life in adult individuals. A total of approximately 160 participants attending the Department of Periodontology will be included. Perio…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Abant Izzet Baysal University
Last updated Apr 30, 2026 15:51 UTC