OVERWEIGHT AND OBESITY

This study is testing whether a low-carbohydrate, high-protein diet works better than a standard diabetes diet for managing type 2 diabetes. For 12 months, 100 adults with type 2 diabetes and overweight will follow one of these two diets, with most of their food provided in meal …

This study is testing the safety and effects of a new weekly injection called AZD9550, both by itself and combined with another drug, AZD6234. It involves about 118 adults who are overweight or have obesity, some with and some without type 2 diabetes. The main goals are to see ho…

This study is testing whether the timing of meals is more effective for weight loss than simply counting calories. Researchers are comparing three approaches: eating all meals within an early 8-hour window, eating within a late 8-hour window, or traditional daily calorie restrict…

This small pilot study is testing whether a 6-month weight loss program delivered through video calls is practical and acceptable for breast cancer survivors who are overweight. Participants attend weekly group sessions focused on diet, exercise, and lifestyle changes, tracking t…

This study aimed to test a new parent training program designed to help children who have both ADHD and weight concerns. The program taught parents strategies to improve their child's planning and self-control skills while promoting healthy habits. Researchers wanted to see if th…

This study is testing whether a comprehensive digital weight loss program, delivered through a patient's online health portal, helps people lose more weight than receiving basic health education. About 250 overweight or obese adults from diverse backgrounds will be randomly assig…

This study is testing whether a daily natural supplement called 'motus' can help people lose weight and body fat over 3 to 6 months. It enrolled 100 adults who are overweight, and participants did not have to follow a specific diet or exercise plan. The main goal is to see if tak…

This study is testing whether a daily fasting schedule can help improve brain function and overall health in older adults who are overweight and noticing memory problems. For 24 weeks, participants will either follow a time-restricted eating plan (fasting for about 16 hours each …

This study is testing if giving breastfeeding mothers a natural dietary supplement called betaine can help prevent babies from gaining weight too quickly in their first year, which is linked to a higher risk of obesity later in life. Researchers will give the supplement or a plac…

This study is testing if a medication called empagliflozin, already used to treat type 2 diabetes, can help people with prediabetes. Researchers want to see if taking the drug for 13 weeks improves how the body handles blood sugar in 60 overweight or obese adults. The goal is to …

This study is testing if a phone-based weight loss and activity coaching program helps people who recently had knee replacement surgery. It compares this program to standard self-management advice to see which is better for losing weight, reducing pain, improving movement, and be…

This study aims to collect and store blood, urine, and tissue samples from 500 adults with obesity. The goal is to create a research bank to help scientists understand why people gain weight, why treatments sometimes fail, and why weight is often regained. This knowledge could le…

This study aims to understand how a specific diet and weight loss affect key hormones in women. Researchers are testing if an 8-week Mediterranean-style diet, designed to help participants lose 5% of their body weight, lowers insulin and testosterone levels. The study involves wo…

This study aims to understand how the body processes fat and sugar at rest, and how this relates to insulin resistance—a key factor in developing type 2 diabetes. Researchers are comparing overweight, sedentary adults with lean, aerobically trained adults, measuring them before a…

This study aims to understand the full health effects of eating oats compared to rice over 6 weeks. It involves 72 adults with conditions like high cholesterol, high blood pressure, or being overweight. Researchers will measure changes in gut bacteria, blood fats, sugar levels, a…

This study is investigating whether eating a meal containing peanuts causes less inflammation in the blood after eating compared to a meal high in saturated fat. Researchers are measuring blood markers in 17 older adults with overweight or obesity after they eat each type of meal…

This study aims to understand how the community of bacteria in a child's gut develops during the first two years of life and how it relates to nutritional problems like stunting, wasting, and obesity. Researchers will follow 70 healthy newborns from rural Pakistan, collecting hea…

This study is testing a new online platform called CONNECT, designed to help more women, Black, and Latino adults join heart disease research. The program sends educational text messages about heart health and clinical trials for one year and helps connect interested people to on…

This study aims to learn how the time of day you exercise and whether you eat beforehand affects how your body burns energy and fat. Researchers will measure these effects in 20 healthy, active adults who are overweight or have obesity. The goal is to gather basic knowledge about…