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Oats vs. rice: which diet lowers cholesterol better?

NCT ID NCT05526092

Disease control Sponsor: University of Turku Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether eating oats for 6 weeks can improve cholesterol, blood pressure, and gut health in people who are overweight or have high cholesterol. Participants will follow a low-gluten diet rich in either oats or rice. Researchers will measure blood fats, inflammation, and gut bacteria to see if oats offer extra benefits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
oats
What this could lead to
If it works, this could show that eating oats regularly helps manage cholesterol and blood pressure without medication.
What could go wrong
This is a small, early-stage dietary study with only 72 people. Results may not apply to everyone, and the effect might be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

72 people

The number who actually took part.

Started

Sep 2022

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 68 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Commits to follow the instructed low-gluten diet for 6 weeks * 30 - 68 years of age * BMI \> 25 kg/m\^2 * High cholesterol (without medication) characterized as total cholesterol \> 5 mmol/l, AND either LDL \> 3 mmol/l OR HDL (men/women) \< 1.0/1.2 mmol/l AND/OR Hypertension (systolic \> 140 mmHg or diastolic \> 90 mmHg). Exclusion Criteria: * Regular medication that can affect the research outcomes (balanced medication for hypertension, hypo-/hyperthyroidism, hormone replacement therapy, and inhaled medicines allowed) * Pregnancy or lactation * Heavy smoking * Recent course of antibiotics (less than 3 months prior to the study)

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Conditions

The condition(s) this trial relates to.

Hypercholesterolemia hyperlipidemia hypertensive disorder Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

High blood pressure High cholesterol/hyperlipidemia Overweight and obesity

Contacts and locations

Locations

  • Food Sciences, Department of Life Technologies, University of Turku

    Turku, Turku, 20500, Finland

  • Institute of Public Health and Clinical Nutrition, University of Eastern Finland

    Kuopio, 70211, Finland

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