OVERWEIGHT AND OBESITY

This study tests a new tablet called DA-302168S to help people lose weight. It is for adults aged 18-75 who are overweight or obese. The study will compare the drug to a placebo to see if it is safe and effective. About 840 people will take part in China.

This early-stage trial tests the safety of an investigational injection called HRS9531 in 48 Chinese adolescents aged 12 to 17 who are obese. Participants receive either the drug or a placebo, and researchers monitor side effects, drug levels in the blood, and changes in weight a…

This pilot study tests whether giving people a choice between two weight management strategies—avoiding tempting foods or learning to resist them—helps them stick with the program better than being assigned a strategy. Sixty adults with overweight or obesity will either choose th…

This 5-year study will follow 2,800 overweight or obese Chinese adults aged 18-60 to see how their health changes over time. Participants will use a smartphone app to track their data and get lifestyle support. The goal is to understand who develops diabetes or complications, and…

This study looks at whether showing people personalized 3D body avatars of their potential weight loss changes how satisfied and committed they feel compared to just seeing numbers on a scale. About 250 adults who want to lose weight will take a one-time online survey. Researcher…

This study will give 10 overweight men a daily pill called ATR-258 for 8 weeks to see how it changes signaling pathways in their muscles. Researchers will take small muscle samples and measure blood sugar control and body composition. The goal is to understand the biology, not to…

This study will follow 800 pregnant women to see if weight stigma and discrimination contribute to complications like gestational diabetes. Researchers will also examine psychological factors such as trauma and eating disorders. The goal is to better understand the link between b…