OROPHARYNGEAL SQUAMOUS CELL CARCINOMA

This study is testing an experimental drug called CUE-101, given before standard surgery or chemoradiation, for people with a specific type of HPV-linked throat cancer. The main goals are to check if the drug is safe and to see if it activates the patient's immune system to bette…

This study is testing a new approach for treating HPV-linked throat cancer. It uses a blood test to see if patients can safely receive a lower dose of radiation and chemotherapy, aiming to control the cancer while reducing side effects. The trial will enroll about 45 adults with …

This study is testing a shorter, lower-dose course of radiation therapy for people with HPV-linked throat cancer who have had robotic surgery. The main goal is to see if this approach can control the cancer while causing fewer side effects and improving patients' quality of life.…

This study is testing a more personalized way to deliver radiation for head and neck cancer. Researchers want to see if using a small biopsy to check lymph nodes can safely allow doctors to skip or reduce radiation to healthy parts of the neck. The goal is to control the cancer j…

This study is testing if adding a new immune-boosting drug (CDX-1140) to an existing immunotherapy (cemiplimab) works better before surgery for advanced head and neck cancer. The goal is to shrink the tumor more effectively, which could lead to less extensive surgery. About 44 pa…

This study is testing whether doctors can safely give less radiation and chemotherapy to people with a specific type of throat cancer linked to HPV. The goal is to see if using a blood test to measure HPV levels can identify patients who can get milder treatment with the same goo…

This study aims to see if a special type of CT scan can work as well as an MRI for diagnosing oral and throat cancers. Currently, patients need both scans, which can delay treatment. Researchers will compare results from both imaging methods in 30 adult patients to determine if t…

This study is testing if adding an investigational drug called BMX-001 to standard symptom care can better prevent severe mouth sores in people receiving combined chemotherapy and radiation for head and neck cancer. About 98 participants will be randomly assigned to receive eithe…

This study aims to find biological markers, or 'fingerprints,' in blood and saliva that can tell when a person has HPV-related throat cancer and when they don't. Researchers will collect samples from 440 people with and without head and neck cancers to compare. The goal is to dis…

This study is testing a blood test to help doctors monitor throat cancer. The test looks for tiny pieces of cancer DNA in the blood to see how well treatment is working and to spot if the cancer comes back early. Researchers are enrolling 250 people with throat cancer, including …

This study aims to understand the genetic differences in throat cancers, particularly those linked to HPV and those that are not, in Taiwanese patients. Researchers will analyze tumor samples from 410 participants to create a detailed genetic map. The goal is to identify patterns…

This study is testing whether a new type of PET/CT scan can better detect damage to neck blood vessels caused by radiation therapy for head and neck cancers. Researchers will compare the new scan to the standard scan in about 20 patients before and after their radiation treatment…