OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for OROPHARYNGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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Blood test may allow safer, Lower-Dose radiation for throat cancer
Disease control Recruiting nowThis study is for people with HPV-related throat cancer. It tests whether a blood test that measures HPV levels can help doctors safely give a lower dose of radiation combined with chemotherapy. The goal is to reduce side effects while still effectively treating the cancer. About…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated May 17, 2026 02:57 UTC
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New drug aims to supercharge immune system against HPV-Positive throat cancer
Disease control Recruiting nowThis study tests an experimental drug called CUE-101 in 30 people with a specific type of HPV-positive throat cancer. The drug is given before standard treatments like surgery or chemoradiation to see if it safely boosts the body's immune cells to fight the cancer. Researchers wi…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 17, 2026 02:55 UTC
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Could less radiation be safer? new trial aims to shrink treatment zones without raising cancer return risk
Disease control Recruiting nowThis study tests whether giving radiation only to high-risk areas after surgery for head and neck cancer can lower side effects without increasing the chance of cancer coming back. About 50 adults with certain types of head and neck cancer will receive a personalized radiation pl…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Olgun Elicin • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Gentler cancer therapy shows promise for HPV-Positive throat cancer patients
Disease control Recruiting nowThis study is for people with a type of throat cancer linked to HPV that has a good outlook. Researchers want to see if using a less intense combination of radiation and chemotherapy can control the cancer just as well as the standard stronger treatment, but with fewer side effec…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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Could a Two-Drug punch before surgery beat head and neck cancer?
Disease control Recruiting nowThis study tests whether adding an experimental drug (CDX-1140) to a standard immunotherapy (cemiplimab) before surgery can shrink advanced head and neck cancers more than the immunotherapy alone. About 44 people with stage III-IV head and neck cancer will receive either the comb…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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Could less radiation mean better life for throat cancer patients?
Disease control Recruiting nowThis study aims to see if a shorter, lower-dose radiation treatment after robotic surgery can improve quality of life for people with HPV-related throat cancer. About 42 adults with intermediate-risk disease will receive a reduced radiation schedule. The main goal is to see if pa…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: University of Utah • Aim: Disease control
Last updated May 05, 2026 11:53 UTC
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Study aims to spare cancer patients from unnecessary radiation side effects
Disease control Recruiting nowThis study is testing a new way to decide which parts of the neck need radiation treatment for head and neck cancer. Doctors will use a small biopsy to check lymph nodes, hoping to avoid radiating healthy areas. The goal is to control the cancer just as well as standard treatment…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: Radboud University Medical Center • Aim: Disease control
Last updated Apr 23, 2026 12:44 UTC
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New CT scan could replace MRI for faster cancer staging
Diagnosis Recruiting nowThis study tests whether a special CT scan (dual-energy CT) works as well as MRI for staging mouth and throat cancers. If it does, patients may need one less scan, speeding up treatment and freeing up MRI machines. The study will enroll 30 adults with these cancers and compare th…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: University Hospital, Strasbourg, France • Aim: Diagnosis
Last updated May 17, 2026 02:44 UTC
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New drug aims to ease painful mouth sores for head and neck cancer patients
Symptom relief Recruiting nowThis study tests whether adding BMX-001 to standard care can reduce severe mouth sores caused by chemoradiation in head and neck cancer patients. About 98 participants will receive either BMX-001 or a placebo alongside their usual treatment. The goal is to improve quality of life…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated May 17, 2026 02:55 UTC
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Mayo clinic hunts for throat cancer clues in blood and saliva
Knowledge-focused Recruiting nowThis study looks for biological markers (biomarkers) in blood, tissue, and saliva that can show if a person has HPV-related throat cancer. Researchers will compare samples from 560 people with and without the disease. The goal is to improve how doctors detect and monitor this can…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 17, 2026 02:56 UTC
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New imaging study reveals hidden vascular damage from radiation in head and neck cancer
Knowledge-focused Recruiting nowThis study uses special PET/CT scans to see how radiation therapy affects blood vessels in the neck of people with head and neck cancers. About 20 adults will get two types of PET scans before and after radiation. The goal is to compare the scans and learn more about radiation's …
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: EARLY_PHASE1 • Sponsor: Emory University • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Taiwanese cancer genetics registry opens to unlock new treatments
Knowledge-focused Recruiting nowThis study is collecting tumor samples from 300 adults with oropharyngeal cancer in Taiwan to analyze their genetic makeup. Researchers hope to find new biomarkers that could lead to better treatments or future clinical trials. Participants must have available tumor tissue and me…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: National Health Research Institutes, Taiwan • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Remote hearing tests could save cancer Patients' hearing
Knowledge-focused Recruiting nowThis study looks at whether offering hearing tests close to home or remotely can help more head and neck cancer patients get their hearing checked during and after treatment. Many patients on cisplatin chemotherapy or radiation may lose hearing, but traveling to the clinic for te…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Emory University • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC
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Blood test may predict throat cancer comeback
Knowledge-focused Recruiting nowThis study follows 220 people with HPV-related throat cancer to see if a simple blood test for HPV DNA and changes in two genes (TRAF3 and CYLD) can predict if the cancer will come back after treatment. Participants will give blood samples and fill out quality-of-life questionnai…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 07, 2026 18:43 UTC
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Blood test could revolutionize throat cancer monitoring
Knowledge-focused Recruiting nowThis study is testing a new blood test that looks for tiny pieces of cancer DNA in the bloodstream of people with throat cancer. The goal is to see if this test can accurately track how well treatment is working and spot cancer returning earlier than current methods. Researchers …
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 05, 2026 11:56 UTC