Blood test may predict throat cancer comeback
NCT ID NCT04564989
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 220 people with HPV-related oropharynx cancer to see if certain gene mutations (TRAF3 and CYLD) and levels of HPV DNA in the blood can predict if the cancer will come back after treatment. Participants give blood samples and fill out quality-of-life questionnaires. The goal is to improve how doctors monitor for recurrence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a blood test that helps doctors know sooner if the cancer is coming back.
- What could go wrong
- This is an observational study, not testing a new treatment. It may not find a reliable way to predict recurrence.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mayo Clinic
ACTIVE_NOT_RECRUITINGRochester, Minnesota, 55905, United States
-
Trident Medical Center (HCA Healthcare )
RECRUITINGNorth Charleston, South Carolina, 29406, United States
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University of North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27599, United States
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